Fleur M. Howells

TL;DR: The largest study to date of cortical gray matter thickness and surface area measures from brain magnetic resonance imaging scans of bipolar disorder patients is performed, revealing previously undetected associations and providing an extensive analysis of potential confounding variables in neuroimaging studies of BD.

TL;DR: The present study provides a robust profile of widespread WM abnormalities in schizophrenia patients worldwide, and is believed to be the first ever large-scale coordinated study of WM microstructural differences in schizophrenia.

TL;DR: This highly powered collaborative effort showed subtle patterns of age-related structural brain abnormalities in MDD, and substantial within-group variance and overlap between groups were observed.

TL;DR: There is a critical gap in the literature of MRI studies in alcohol-exposed children under 5 years of age across all MRI modalities, and the dynamic nature of brain maturation and appreciation of the effects of alcohol exposure on the developing trajectory of the structural and functional network argue for the prioritisation of studies that include a longitudinal approach.

TL;DR: The effects of methamphetamine on dopaminergic pathways are reviewed, with focus on its ability to increase glutamate release in the cortex and it is proposed that cortical GABAergic interneurons are particularly vulnerable to glutamate overflow as a result of subcellular location of NMDA receptors on interneerons in the cerebral cortex.