K
Karina Dalsgaard Sørensen
Researcher at Aarhus University Hospital
Publications - 137
Citations - 5937
Karina Dalsgaard Sørensen is an academic researcher from Aarhus University Hospital. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 34, co-authored 112 publications receiving 4553 citations. Previous affiliations of Karina Dalsgaard Sørensen include Aarhus University.
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Journal ArticleDOI
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Fredrick R. Schumacher,Ali Amin Al Olama,Sonja I. Berndt,Sara Benlloch,Mahbubl Ahmed,Edward J. Saunders,Tokhir Dadaev,Daniel Leongamornlert,Ezequiel Anokian,Clara Cieza-Borrella,Chee Goh,Mark N. Brook,Xin Sheng,Laura Fachal,Joe Dennis,Jonathan Tyrer,Kenneth Muir,Kenneth Muir,Artitaya Lophatananon,Artitaya Lophatananon,Victoria L. Stevens,Susan M. Gapstur,Brian D. Carter,Catherine M. Tangen,Phyllis J. Goodman,Ian M. Thompson,Jyotsna Batra,Jyotsna Batra,Suzanne K. Chambers,Suzanne K. Chambers,Leire Moya,Leire Moya,Judith A. Clements,Judith A. Clements,Lisa G. Horvath,Wayne D. Tilley,Gail P. Risbridger,Gail P. Risbridger,Henrik Grönberg,Markus Aly,Tobias Nordström,Paul D.P. Pharoah,Nora Pashayan,Johanna Schleutker,Teuvo L.J. Tammela,Csilla Sipeky,Anssi Auvinen,Demetrius Albanes,Stephanie J. Weinstein,Alicja Wolk,Alicja Wolk,Niclas Håkansson,Catharine M L West,Alison M. Dunning,Neil G. Burnet,Lorelei A. Mucci,Edward Giovannucci,Gerald L. Andriole,Olivier Cussenot,Geraldine Cancel-Tassin,Stella Koutros,Laura E. Beane Freeman,Karina Dalsgaard Sørensen,Torben F. Ørntoft,Michael Borre,Lovise Maehle,Eli Marie Grindedal,David E. Neal,David E. Neal,David E. Neal,Jenny L Donovan,Freddie C. Hamdy,Richard M. Martin,Ruth C. Travis,Timothy J. Key,Robert J. Hamilton,Neil E. Fleshner,Antonio Finelli,Sue A. Ingles,Mariana C. Stern,Barry S. Rosenstein,Sarah L. Kerns,Harry Ostrer,Yong-Jie Lu,Hongwei Zhang,Ninghan Feng,Xueying Mao,Xin Guo,Guomin Wang,Zan Sun,Graham G. Giles,Melissa C. Southey,Robert J. MacInnis,Robert J. MacInnis,Liesel M. FitzGerald,Liesel M. FitzGerald,Adam S. Kibel,Bettina F. Drake,Ana Vega,Antonio Gómez-Caamaño,Robert Szulkin,Martin Eklund,Manolis Kogevinas,Javier Llorca,Gemma Castaño-Vinyals,Kathryn L. Penney,Meir J. Stampfer,Jong Y. Park,Thomas A. Sellers,Hui Yi Lin,Janet L. Stanford,Janet L. Stanford,Cezary Cybulski,Dominika Wokołorczyk,Jan Lubinski,Elaine A. Ostrander,Milan S. Geybels,Børge G. Nordestgaard,Sune F. Nielsen,Maren Weischer,Rasmus Bisbjerg,Martin Andreas Røder,Peter Iversen,Hermann Brenner,Katarina Cuk,Bernd Holleczek,Christiane Maier,Manuel Luedeke,Thomas J. Schnoeller,Jeri Kim,Christopher J. Logothetis,Esther M. John,Esther M. John,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Marta Cardoso,Susan L. Neuhausen,Linda Steele,Yuan Chun Ding,Kim De Ruyck,Gert De Meerleer,Piet Ost,Azad Hassan Abdul Razack,Jasmine Lim,Soo Hwang Teo,Daniel W. Lin,Daniel W. Lin,Lisa F. Newcomb,Lisa F. Newcomb,Davor Lessel,Marija Gamulin,Tomislav Kuliš,Radka Kaneva,Nawaid Usmani,Nawaid Usmani,Sandeep Singhal,Sandeep Singhal,Chavdar Slavov,Vanio Mitev,Matthew Parliament,Matthew Parliament,Frank Claessens,Steven Joniau,Thomas Van den Broeck,Samantha E.T. Larkin,Paul A. Townsend,Claire Aukim-Hastie,Manuela Gago Dominguez,Jose Esteban Castelao,Maria Elena Martinez,Monique J. Roobol,Guido Jenster,Ron H.N. van Schaik,Florence Menegaux,Thérèse Truong,Yves Akoli Koudou,Jianfeng Xu,Kay-Tee Khaw,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hardev Pandha,Agnieszka Michael,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Sara Lindström,Constance Turman,Jing Ma,David J. Hunter,Elio Riboli,A. Siddiq,Federico Canzian,Laurence N. Kolonel,Loic Le Marchand,Robert N. Hoover,Mitchell J. Machiela,Zuxi Cui,Peter Kraft,Christopher I. Amos,David V. Conti,Douglas F. Easton,Fredrik Wiklund,Stephen J. Chanock,Brian E. Henderson,Zsofia Kote-Jarai,Christopher A. Haiman,Rosalind A. Eeles +207 more
TL;DR: A large meta-analysis combining genome-wide and custom high-density genotyping array data identifies 63 new susceptibility loci for prostate cancer, enhancing fine-mapping efforts and providing insights into the underlying biology of PrCa1.
Journal ArticleDOI
A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation
Hila Gingold,Disa Tehler,Nanna R. Christoffersen,Morten Muhlig Nielsen,Fazila Asmar,Susanne M. Kooistra,Nicolaj S. Christophersen,Lise Lotte Christensen,Michael Borre,Karina Dalsgaard Sørensen,Lars Dyrskjot Andersen,Claus L. Andersen,Esther Hulleman,Thomas Wurdinger,Elisabeth Ralfkiaer,Kristian Helin,Kirsten Grønbæk,Torben F. Ørntoft,Sebastian M. Waszak,Orna Dahan,Jakob Skou Pedersen,Anders H. Lund,Yitzhak Pilpel +22 more
TL;DR: The existence of two distinct translation programs that operate during proliferation and differentiation are described, suggesting the existence of transcriptional programs coordinating tRNA supply and demand.
Journal ArticleDOI
An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.
Dorte B. Bekker-Jensen,Christian D. Kelstrup,Tanveer S. Batth,Sara Larsen,Christa Haldrup,Jesper B. Bramsen,Karina Dalsgaard Sørensen,Søren Høyer,Torben F. Ørntoft,Claus L. Andersen,Michael L. Nielsen,Jesper V. Olsen +11 more
TL;DR: A classical two-dimensional high-resolution reversed-phase peptide fractionation scheme is modified and optimized to provide sufficient peak capacity to saturate the sequencing speed of modern MS instruments.
Journal ArticleDOI
Next-generation sequencing of RNA and DNA isolated from paired fresh-frozen and formalin-fixed paraffin-embedded samples of human cancer and normal tissue.
Jakob Hedegaard,Kasper Thorsen,Mette Katrine Lund,Anne-Mette K. Hein,Stephen Hamilton-Dutoit,Søren Vang,Iver Nordentoft,Karin Birkenkamp-Demtröder,Mogens Kruhøffer,Henrik Hager,Bjarne Knudsen,Claus L. Andersen,Karina Dalsgaard Sørensen,Jakob Skou Pedersen,Torben F. Ørntoft,Lars Dyrskjøt +15 more
TL;DR: The results are promising and suggest that NGS can be used to study FFPE specimens in both prospective and retrospective archive-based studies in which FF specimens are not available.
Journal ArticleDOI
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
Zsofia Kote-Jarai,Olama Aaa.,G.G. Giles,G.G. Giles,Gianluca Severi,Gianluca Severi,Johanna Schleutker,Maren Weischer,Daniele Campa,Elio Riboli,Timothy J. Key,Henrik Grönberg,David J. Hunter,Peter Kraft,Michael J. Thun,Sue A. Ingles,Stephen J. Chanock,Stephen J. Chanock,Demetrius Albanes,Richard B. Hayes,David E. Neal,David E. Neal,Freddie C. Hamdy,Jenny L Donovan,Paul D.P. Pharoah,Fredrick R. Schumacher,Brian E. Henderson,Janet L. Stanford,Janet L. Stanford,Elaine A. Ostrander,Karina Dalsgaard Sørensen,Thilo Dörk,Gerald L. Andriole,Joanne L. Dickinson,Cezary Cybulski,Jan Lubinski,Amanda B. Spurdle,Judith A. Clements,Suzanne K. Chambers,Joanne F. Aitken,Gardiner Raf.,S. N. Thibodeau,D J Schaid,Esther M. John,Esther M. John,Christiane Maier,W. Vogel,Kathleen A. Cooney,Jong Y. Park,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hermann Brenner,Tomonori Habuchi,Zhang H-W.,Lu Y-J.,Radka Kaneva,Kenneth Muir,Sara Benlloch,Daniel Leongamornlert,Ed Saunders,Malgorzata Tymrakiewicz,N. Mahmud,Michelle Guy,Lynne T. O'Brien,R A Wilkinson,Amanda L. Hall,E J Sawyer,Tokhir Dadaev,Jonathan J. Morrison,David P. Dearnaley,David P. Dearnaley,Alan Horwich,Alan Horwich,Robert Huddart,Robert Huddart,Vincent Khoo,Vincent Khoo,Chris Parker,Chris Parker,N. van As,C.R.J. Woodhouse,A. Thompson,Timothy J. Christmas,Chris Ogden,Colin Cooper,Aritaya Lophatonanon,Melissa C. Southey,John L. Hopper,Dallas R. English,Dallas R. English,T. Wahlfors,Tammela Tlj.,Peter Klarskov,Børge G. Nordestgaard,Martin Andreas Røder,Anne Tybjærg-Hansen,Stig E. Bojesen,Ruth C. Travis,Federico Canzian,Rudolph Kaaks,Fredrik Wiklund,Markus Aly,Sara Lindström,W. R. Diver,Susan M. Gapstur,Mariana C. Stern,Roman Corral,Jarmo Virtamo,Angela Cox,Christopher A. Haiman,Loic Le Marchand,Liesel M. FitzGerald,Suzanne Kolb,Erika M. Kwon,Danielle M. Karyadi,Torben F. Ørntoft,Michael Borre,Andreas Meyer,Jürgen Serth,Meredith Yeager,Sonja I. Berndt,James R. Marthick,Briony Patterson,Dominika Wokołorczyk,Jyotsna Batra,Felicity Lose,Shannon K. McDonnell,Amit Joshi,A Shahabi,Antje E. Rinckleb,A Ray,T A Sellers,Lin H-Y.,Robert A. Stephenson,J. M. Farnham,Heiko Müller,Dietrich Rothenbacher,Norihiko Tsuchiya,Shintaro Narita,Cao G-W.,C. Slavov,Vanio Mitev,Douglas F. Easton,Rosalind A. Eeles,Rosalind A. Eeles +144 more
TL;DR: The results of stage 3 are reported, in which 1,536 SNPs are evaluated in 4,574 individuals with prostate cancer (cases) and 4,164 controls and a SNP in TERT more strongly associated with PrCa than that previously reported is identified.