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Virpi Lindi
Researcher at University of Eastern Finland
Publications - 92
Citations - 5052
Virpi Lindi is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Body fat percentage & Body mass index. The author has an hindex of 34, co-authored 91 publications receiving 4377 citations. Previous affiliations of Virpi Lindi include University of Jyväskylä & University of Exeter.
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Journal ArticleDOI
Genome-wide associations for birth weight and correlations with adult disease
Momoko Horikoshi,Robin N Beaumont,Felix R. Day,Nicole M. Warrington,Nicole M. Warrington,Marjolein N. Kooijman,Juan Fernández-Tajes,Bjarke Feenstra,Natalie R. van Zuydam,Kyle J. Gaulton,Kyle J. Gaulton,Niels Grarup,Jonathan P. Bradfield,David P. Strachan,Ruifang Li-Gao,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Eskil Kreiner,Rico Rueedi,Rico Rueedi,Leo-Pekka Lyytikäinen,Diana L. Cousminer,Diana L. Cousminer,Diana L. Cousminer,Ying Wu,Elisabeth Thiering,Carol A. Wang,Christian Theil Have,Jouke-Jan Hottenga,Natalia Vilor-Tejedor,Peter K. Joshi,Eileen Tai-Hui Boh,Ioanna Ntalla,Ioanna Ntalla,Niina Pitkänen,Anubha Mahajan,Elisabeth M. van Leeuwen,Raimo Joro,Vasiliki Lagou,Vasiliki Lagou,Michael Nodzenski,Louise A. Diver,Krina T. Zondervan,Mariona Bustamante,Pedro Marques-Vidal,Josep M. Mercader,Amanda J. Bennett,Nilufer Rahmioglu,Dale R. Nyholt,Ronald C.W. Ma,Claudia H. T. Tam,Wing Hung Tam,Santhi K. Ganesh,Frank J.A. van Rooij,Samuel E. Jones,Po-Ru Loh,Katherine S. Ruth,Marcus A. Tuke,Jessica Tyrrell,Andrew R. Wood,Hanieh Yaghootkar,Denise M. Scholtens,Lavinia Paternoster,Inga Prokopenko,Inga Prokopenko,Peter Kovacs,Mustafa Atalay,Sara M. Willems,Kalliope Panoutsopoulou,Xu Wang,Lisbeth Carstensen,Frank Geller,Katharina E. Schraut,Mario Murcia,Catharina E. M. van Beijsterveldt,Gonneke Willemsen,Emil V. R. Appel,Cilius Esmann Fonvig,Cæcilie Trier,Carla M. T. Tiesler,Marie Standl,Zoltán Kutalik,Zoltán Kutalik,Sílvia Bonàs-Guarch,David M. Hougaard,Friman Sánchez,David Torrents,Johannes Waage,Mads V. Hollegaard,Hugoline G. de Haan,Frits R. Rosendaal,Carolina Medina-Gomez,Susan M. Ring,Gibran Hemani,George McMahon,Neil R. Robertson,Christopher J. Groves,Claudia Langenberg,Jian'an Luan,Robert A. Scott,Jing Hua Zhao,Frank D. Mentch,Scott M. MacKenzie,Rebecca M. Reynolds,William L. Lowe,Anke Tönjes,Michael Stumvoll,Virpi Lindi,Timo A. Lakka,Cornelia M. van Duijn,Wieland Kiess,Antje Körner,Thorkild I. A. Sørensen,Harri Niinikoski,Katja Pahkala,Olli T. Raitakari,Eleftheria Zeggini,George Dedoussis,Yik Ying Teo,Seang-Mei Saw,Mads Melbye,Mads Melbye,Mads Melbye,Harry Campbell,James F. Wilson,Martine Vrijheid,Eco J. C. de Geus,Eco J. C. de Geus,Dorret I. Boomsma,Haja N. Kadarmideen,Jens-Christian Holm,Torben Hansen,Sylvain Sebert,Sylvain Sebert,Andrew T. Hattersley,Lawrence J. Beilin,John P. Newnham,Craig E. Pennell,Joachim Heinrich,Linda S. Adair,Judith B. Borja,Karen L. Mohlke,Johan G. Eriksson,Johan G. Eriksson,Elisabeth Widen,Mika Kähönen,Jorma Viikari,Terho Lehtimäki,Peter Vollenweider,Klaus Bønnelykke,Hans Bisgaard,Dennis O. Mook-Kanamori,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,Charlotta Pisinger,Oluf Pedersen,Christine Power,Elina Hyppönen,Elina Hyppönen,Nicholas J. Wareham,Hakon Hakonarson,Eleanor Davies,Brian R. Walker,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Struan F.A. Grant,Allan Vaag,Allan Vaag,Debbie A Lawlor,Timothy M. Frayling,George Davey Smith,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Ken K. Ong,Janine F. Felix,Nicholas J. Timpson,John R. B. Perry,David M. Evans,David M. Evans,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Rachel M. Freathy,Rachel M. Freathy +185 more
TL;DR: In this paper, the authors performed a meta-analysis of birth weight in 153,781 individuals, identifying 60 loci where fetal genotype was associated with birth weight (P < 5.5×10−8).
Journal ArticleDOI
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Momoko Horikoshi,Hanieh Yaghootkar,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Ulla Sovio,Ulla Sovio,H. Rob Taal,Branwen J. Hennig,Jonathan P. Bradfield,Beate St Pourcain,David M. Evans,Pimphen Charoen,Pimphen Charoen,Marika Kaakinen,Diana L. Cousminer,Terho Lehtimäki,Eskil Kreiner-Møller,Nicole M. Warrington,Mariona Bustamante,Bjarke Feenstra,Diane J. Berry,Elisabeth Thiering,Thiemo Pfab,Thiemo Pfab,Sheila J. Barton,Beverley M. Shields,Marjan Kerkhof,Elisabeth M. van Leeuwen,Anthony J. C. Fulford,Zoltán Kutalik,Zoltán Kutalik,Jing Hua Zhao,Marcel den Hoed,Anubha Mahajan,Virpi Lindi,Liang Kee Goh,Jouke-Jan Hottenga,Ying Wu,Olli T. Raitakari,Marie Neergaard Harder,Aline Meirhaeghe,Aline Meirhaeghe,Aline Meirhaeghe,Ioanna Ntalla,Rany M. Salem,Rany M. Salem,Karen A. Jameson,Kaixin Zhou,Dorota Monies,Vasiliki Lagou,Mirna Kirin,Jani Heikkinen,Linda S. Adair,Fowzan S. Alkuraya,Ali Al-Odaib,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Ehm A. Andersson,Amanda J. Bennett,Alexandra I. F. Blakemore,Jessica L. Buxton,Jean Dallongeville,Jean Dallongeville,Jean Dallongeville,Shikta Das,Eco J. C. de Geus,Xavier Estivill,Claudia Flexeder,Philippe Froguel,Philippe Froguel,Philippe Froguel,Frank Geller,Keith M. Godfrey,Keith M. Godfrey,Frédéric Gottrand,Christopher J. Groves,Torben Hansen,Torben Hansen,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Mads V. Hollegaard,David M. Hougaard,Elina Hyppönen,Hazel Inskip,Aaron Isaacs,Aaron Isaacs,Torben Jørgensen,Christina Kanaka-Gantenbein,John P. Kemp,Wieland Kiess,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Norman Klopp,Bridget A. Knight,Christopher W. Kuzawa,George McMahon,John P. Newnham,Harri Niinikoski,Ben A. Oostra,Louise Pedersen,Dirkje S. Postma,Susan M. Ring,Fernando Rivadeneira,Neil R. Robertson,Sylvain Sebert,Sylvain Sebert,Olli Simell,Torsten Slowinski,Carla M. T. Tiesler,Anke Tönjes,Allan Vaag,Allan Vaag,Jorma Viikari,Jacqueline M. Vink,Nadja Hawwa Vissing,Nicholas J. Wareham,Gonneke Willemsen,Daniel R. Witte,Haitao Zhang,Jianhua Zhao,James F. Wilson,Michael Stumvoll,Andrew M. Prentice,Brian F. Meyer,Ewan R. Pearson,Colin Boreham,Cyrus Cooper,Matthew W. Gillman,George Dedoussis,Luis A. Moreno,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Maiju Saarinen,Karen L. Mohlke,Dorret I. Boomsma,Seang-Mei Saw,Seang-Mei Saw,Timo A. Lakka,Antje Körner,Ruth J. F. Loos,Ken K. Ong,Peter Vollenweider,Cornelia M. van Duijn,Gerard H. Koppelman,Andrew T. Hattersley,John W. Holloway,Berthold Hocher,Joachim Heinrich,Chris Power,Mads Melbye,Mònica Guxens,Craig E. Pennell,Klaus Bønnelykke,Hans Bisgaard,Johan G. Eriksson,Elisabeth Widen,Hakon Hakonarson,André G. Uitterlinden,Anneli Pouta,Anneli Pouta,Debbie A Lawlor,George Davey Smith,Timothy M. Frayling,Mark I. McCarthy,Mark I. McCarthy,Struan F.A. Grant,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Nicholas J. Timpson,Inga Prokopenko,Rachel M. Freathy,Rachel M. Freathy +174 more
TL;DR: The number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking, are extended and highlight genetic links between fetal growth and postnatal growth and metabolism.
Journal ArticleDOI
Promoter Polymorphisms of the TNF-α (G-308A) and IL-6 (C-174G) Genes Predict the Conversion From Impaired Glucose Tolerance to Type 2 Diabetes: The Finnish Diabetes Prevention Study
Agata Kubaszek,Jussi Pihlajamäki,Vladislav Komarovski,Virpi Lindi,Jaana Lindström,Johan G. Eriksson,Timo T. Valle,Helena Hämäläinen,Pirjo Ilanne-Parikka,Sirkka Keinänen-Kiukaanniemi,Jaakko Tuomilehto,Matti Uusitupa,Markku Laakso +12 more
TL;DR: The -308A allele of the promoter polymorphism (G-308A) of the TNF-alpha gene is a predictor for the conversion from IGT to type 2 diabetes and seems to have a gene-gene interaction with the C-174C genotype of the IL-6 gene.
Journal ArticleDOI
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.
Janine F. Felix,Jonathan P. Bradfield,Claire Monnereau,Ralf J. P. van der Valk,Evie Stergiakouli,Alessandra Chesi,Romy Gaillard,Bjarke Feenstra,Elisabeth Thiering,Eskil Kreiner-Møller,Anubha Mahajan,Pitkänen Niina Pitkänen,Pitkänen Niina Pitkänen,Raimo Joro,Alana Cavadino,Alana Cavadino,Ville Huikari,Steve Franks,Maria M. Groen-Blokhuis,Diana L. Cousminer,Julie A. Marsh,Terho Lehtimäki,John A. Curtin,Jesús Vioque,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Ronny Myhre,Thomas S. Price,Vilor-Tejedor Natalia Vilor-Tejedor,Loic Yengo,Niels Grarup,Ioanna Ntalla,Ioanna Ntalla,Wei Ang,Mustafa Atalay,Hans Bisgaard,Alexandra I. F. Blakemore,Amélie Bonnefond,Lisbeth Carstensen,Johan G. Eriksson,Claudia Flexeder,Lude Franke,Frank Geller,Mandy Geserick,Anna-Liisa Hartikainen,Claire M. A. Haworth,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Jens-Christian Holm,Momoko Horikoshi,Jouke-Jan Hottenga,Jinyan Huang,Haja N. Kadarmideen,Mika Kähönen,Wieland Kiess,Hanna Maaria Lakka,Timo A. Lakka,Alexandra M. Lewin,Liming Liang,Leo-Pekka Lyytikäinen,Baoshan Ma,Per Magnus,Shana E. McCormack,George McMahon,Frank D. Mentch,Christel M. Middeldorp,Clare S. Murray,Katja Pahkala,Tune H. Pers,Tune H. Pers,Roland Pfäffle,Dirkje S. Postma,Christine Power,Angela Simpson,Verena Sengpiel,Carla M. T. Tiesler,Maties Torrent,André G. Uitterlinden,Joyce B. J. van Meurs,Rebecca K. Vinding,Johannes Waage,Jane Wardle,Eleftheria Zeggini,Babette S. Zemel,George Dedoussis,Oluf Pedersen,Philippe Froguel,Jordi Sunyer,Robert Plomin,Bo Jacobsson,Bo Jacobsson,Torben Hansen,Juan R. González,Adnan Custovic,Olli T. Raitakari,Craig E. Pennell,Widén Elisabeth Widén,Dorret I. Boomsma,Gerard H. Koppelman,Sylvain Sebert,Marjo-Riitta Järvelin,Elina Hyppönen,Mark I. McCarthy,Mark I. McCarthy,Virpi Lindi,Niinikoski Harri,Antje Körner,Klaus Bønnelykke,Joachim Heinrich,Mads Melbye,Mads Melbye,Fernando Rivadeneira,Hakon Hakonarson,Hakon Hakonarson,Susan M. Ring,George Davey Smith,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Nicholas J. Timpson,Struan F.A. Grant,Vincent W. V. Jaddoe,Heidi J. Kalkwarf,Joan M. Lappe,Vicente Gilsanz,Sharon E. Oberfield,John A. Shepherd,Andrea Kelly +127 more
TL;DR: A meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores, identifies three novel loci that likely represent age-related differences in strength of the associations with bodymass index.
Genome-wide associations for birth weight and correlations with adult disease
Momoko Horikoshi,Robin N Beaumont,Felix R. Day,Nicole M. Warrington,Marjolein N. Kooijman,Juan Fernández-Tajes,Bjarke Feenstra,Natalie R. van Zuydam,Kyle J. Gaulton,Niels Grarup,Jonathan P. Bradfield,David P. Strachan,Ruifang Li-Gao,Tarunveer S. Ahluwalia,Eskil Kreiner,Rico Rueedi,Leo-Pekka Lyytikäinen,Diana L. Cousminer,Ying Wu,Elisabeth Thiering,Carol A. Wang,Christian Theil Have,Jouke-Jan Hottenga,Natalia Vilor-Tejedor,Peter K. Joshi,Eileen Tai-Hui Boh,Ioanna Ntalla,Niina Pitkänen,Anubha Mahajan,Elisabeth M. van Leeuwen,Raimo Joro,Vasiliki Lagou,Michael Nodzenski,Louise A. Diver,Krina T. Zondervan,Mariona Bustamante,Pedro Marques-Vidal,Josep M. Mercader,Amanda J. Bennett,Nilufer Rahmioglu,Dale R. Nyholt,Ronald C.W. Ma,Claudia H. T. Tam,Wing Hung Tam,Santhi K. Ganesh,Frank J. A. van Rooij,Samuel E. Jones,Po-Ru Loh,Katherine S. Ruth,Marcus A. Tuke,Jessica Tyrrell,Andrew R. Wood,Hanieh Yaghootkar,Denise M. Scholtens,Lavinia Paternoster,Inga Prokopenko,Peter Kovacs,Mustafa Atalay,Sara M. Willems,Kalliope Panoutsopoulou,Xu Wang,Lisbeth Carstensen,Frank Geller,Katharina E. Schraut,Mario Murcia,Catharina E. M. van Beijsterveldt,Gonneke Willemsen,Emil V. R. Appel,Cilius Esmann Fonvig,Cæcilie Trier,Carla M. T. Tiesler,Marie Standl,Zoltán Kutalik,Sílvia Bonàs-Guarch,David M. Hougaard,Friman Sánchez,David Torrents,Johannes Waage,Mads V. Hollegaard,Hugoline G. de Haan,Frits R. Rosendaal,Carolina Medina-Gomez,Susan M. Ring,Gibran Hemani,George McMahon,Neil R. Robertson,Christopher J. Groves,Claudia Langenberg,Jian'an Luan,Robert A. Scott,Jing Hua Zhao,Frank D. Mentch,Scott M. MacKenzie,Rebecca M. Reynolds,William L. Lowe,Anke Toenjes,Michael Stumvoll,Virpi Lindi,Timo A. Lakka,Cornelia M. van Duijn,Wieland Kiess,Antje Koerner,Thorkild I. A. Sørensen,Harri Niinikoski,Katja Pahkala,Olli T. Raitakari,Eleftheria Zeggini,George Dedoussis,Yik Ying Teo,Seang-Mei Saw,Mads Melbye,Harry Campbell,James F. Wilson,Martine Vrijheid,Eco J. C. de Geus,Dorret I. Boomsma,Haja N. Kadarmideen,Jens-Christian Holm,Torben Hansen,Sylvain Sebert,Andrew T. Hattersley,Lawrence J. Beilin,John P. Newnham,Craig E. Pennell,Joachim Heinrich,Linda S. Adair,Judith B. Borja,Karen L. Mohlke,Johan G. Eriksson,Elisabeth Widen,Mika Kähönen,Jorma Viikari,Terho Lehtimäki,Peter Vollenweider,Klaus Bønnelykke,Hans Bisgaard,Dennis O. Mook-Kanamori,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,Charlotta Pisinger,Oluf Pedersen,Christine Power,Elina Hyppoenen,Nicholas J. Wareham,Hakon Hakonarson,Eleanor Davies,Brian R. Walker,Vincent W. V. Jaddoe,Marjo-Riitta Jaervelin,Struan F.A. Grant,Allan Vaag,Debbie A Lawlor,Timothy M. Frayling,George Davey Smith,Andrew P. Morris,Ken K. Ong,Janine F. Felix,Nicholas J. Timpson,John R. B. Perry,David M. Evans,Mark I. McCarthy,Rachel M. Freathy +162 more