Nikki Graham

TL;DR: The results identify a genetic locus associated with estrogen receptor negative breast cancer subtypes in multiple populations in multiple population of women.

TL;DR: Three new breast cancer risk loci are identified at 12p11, 12q24 and 21q21, which lie in regions that contain strong plausible candidate genes: PTHLH has a crucial role in mammary gland development and the establishment of bone metastasis in breast cancer, and NRIP1 encodes an ER cofactor and has a role in the regulation of breast cancer cell growth.

TL;DR: It is shown that collagen IV mutations, including COL4A5, frequently underlie FSGS and should be considered, particularly with a positive family history, as well as in patients with a history of renal disease.

TL;DR: The largest meta-analysis of ER-negative disease to date, comprising 4754 ER- negative cases and 31 663 controls from three GWAS, identified two novel loci for breast cancer at 20q11 and 6q14 and confirmed three known loci associated with ER- Negative, triple negative and ER-positive breast cancer.

TL;DR: Six single-nucleotide polymorphisms are identified, significantly associated with the risk of triple-negative breast cancer, providing convincing evidence of genetic susceptibility for triple- negative breast cancer.