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Olivier Elemento
Researcher at Cornell University
Publications - 596
Citations - 38936
Olivier Elemento is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 82, co-authored 471 publications receiving 27739 citations. Previous affiliations of Olivier Elemento include Princeton University & Max Planck Society.
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Serial ctDNA evaluation to predict clinical progression in patients with advanced urothelial carcinoma.
Kyrillus S. Shohdy,Dario Martin Villamar,Yen Cao,Janson Trieu,Kristin Price,Rebecca Nagy,Scott T. Tagawa,Ana M. Molina,Cora N. Sternberg,David M. Nanus,Petros Grivas,Guru Sonpavde,Juan Miguel Mosquera,Olivier Elemento,Nicholas J. Vogelzang,Bishoy Faltas +15 more
TL;DR: Serial ctDNA provided insights into the clonal dynamics of treatment resistance, including the acquisition of ERBB2 S653C resistance mutation at the time of PD on lapatinib, and has the potential to guide future adaptive therapy paradigms.
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PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma.
Shelby Sloan,Fiona Brown,Mackenzie E. Long,Christoph Weigel,Shirshak Koirala,Ji Hyun Chung,Betsy A Pray,Linda Villagomez,Claire Hinterschied,Anuvrat Sircar,J. Helmig-Mason,Alexander Prouty,Eric Brooks,Youssef Youssef,W Hanel,Samir Parekh,Wing Keung Chan,Zhengming Chen,Rosa Lapalombella,Lalit Sehgal,Kris Vaddi,Peggy Scherle,Selina Chen-Kiang,Maurizio Di Liberto,Olivier Elemento,Cem Meydan,Jonathan Foox,Daniel Butler,Christopher E. Mason,Robert A. Baiocchi,Lapo Alinari +30 more
TL;DR: In this paper , the anti-tumor activity of protein arginine methyltransferase 5 (PRMT5) inhibition in MCL using integrated transcriptomics of in vitro and in vivo models of MCL.
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Abstract P5-05-02: Extracellular vesicles from obese human breast adipose tissue promote breast cancer cell proliferation by increasing mitochondrial mass and stimulating mitochondrial respiration
Shuchen Liu,Alberto Benito-Martin,Phoebe Piloco,Catherine Liu,Paul Paik,Jason A. Spector,Fanny A. Pelissier Vatter,David Lyden,David M. Otterburn,Leslie E. Cohen,Olivier Elemento,Rohan Bareja,Leona Cohen-Gould,Samuel Calto,Kristy A. Brown +14 more
TL;DR: Breast adipose tissue EVs from overweight and obese women stimulate the proliferation of ER+ breast cancer cells by increasing mitochondrial mass and stimulating mitochondrial respiration, providing a novel mechanistic link between obesity and breast cancer.
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The identification of CELSR3 and other potential cell surface targets in neuroendocrine prostate cancer
Lucie Van Emmenis,Sheng-Yu Ku,Kaitlyn Gayvert,Jonathan Branch,Nicholas J. Brady,Subhasree Basu,Michael Russell,Joanna Cyrta,Aram Vosoughi,Verena Sailer,Hussein Alnajar,Etienne Dardenne,Elena Koumis,Loredana Puca,Brian D. Robinson,Michael D. Feldkamp,Ann-Marie Winkis,Nate Majewski,Brent A. Rupnow,Marco M. Gottardis,Olivier Elemento,Mark A. Rubin,Himisha Beltran,David S. Rickman +23 more
TL;DR: In this paper , a multi-step bioinformatic pipeline was developed to identify NEPC-specific, over-expressed gene transcripts that encode cell surface proteins, including CEACAM5 and CESLR3.
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Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer
Martin Bakht,Yasutaka Yamada,Sheng-Yu Ku,Varadha Balaji Venkadakrishnan,Joshua A. Korsen,Teja Kalidindi,Kei Mizuno,Ji-Heui Seo,Francesca Khani,Olivier Elemento,Henry W. Long,Alain Chaglassian,Nagavarakishore Pillarsetty,Jason S. Lewis,Matthew L. Freedman,Anthony P. Belanger,Quang-Dé Nguyen,Himisha Beltran +17 more