O
Olivier Elemento
Researcher at Cornell University
Publications - 596
Citations - 38936
Olivier Elemento is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 82, co-authored 471 publications receiving 27739 citations. Previous affiliations of Olivier Elemento include Princeton University & Max Planck Society.
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Book ChapterDOI
Analyzing DNA Methylation Patterns During Tumor Evolution.
Heng Pan,Olivier Elemento +1 more
TL;DR: A comprehensive computational methodology to thoroughly analyze DNA methylation patterns during tumor evolution based on bisulfite converted sequencing data, including intra-tumor methylation heterogeneity is described.
Book ChapterDOI
Drug-Induced Expression-Based Computational Repurposing of Small Molecules Affecting Transcription Factor Activity.
Kaitlyn Gayvert,Olivier Elemento +1 more
TL;DR: CRAFTT combines transcription factor target gene sets with drug-induced expression profiling to identify small molecules that can perturb transcription factor activity and derive a modulation index (MI) and prioritize predictions.
Journal ArticleDOI
KLF4: A new player in plasma cell development.
TL;DR: The existence of a new master regulator of plasma cell development is suggested using analysis of expression profiles and it is shown that the transcription factor KLF4 is expressed in human healthy bone marrow plasma cells and increased production of early PC and LLPC generation by reducing cell death.
Journal ArticleDOI
Toward Artificial Intelligence-Driven Pathology Assessment for Hematologic Malignancies.
TL;DR: This study provides new insights into the pathobiology of MDS and paves the way for increased use of artificial intelligence for the assessment and diagnosis of hematological malignancies.
Journal ArticleDOI
Circulating tumor DNA (ctDNA) to detect neuroendocrine prostate cancer genomic and DNA methylation changes.
Himisha Beltran,Alessandro Romanel,Vincenza Conteduca,Nicola Casiraghi,Michael Sigouros,Gian Marco Franceschini,Tarcisio Fedrizzi,Sheng-Yu Ku,Alicia Alonso,Juan Miguel Mosquera,Emma Dann,Andrea Sboner,Jenny Xiang,Olivier Elemento,David M. Nanus,Scott T. Tagawa,Matteo Benelli,Francesca Demichelis +17 more
TL;DR: A small number of animals have shown the ability to undergo transformation to castration resistant prostate cancers through loss of androgen receptor signaling dependence, and this may manifest as transformation toCastration resistant neur...