O
Olivier Elemento
Researcher at Cornell University
Publications - 596
Citations - 38936
Olivier Elemento is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 82, co-authored 471 publications receiving 27739 citations. Previous affiliations of Olivier Elemento include Princeton University & Max Planck Society.
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SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy
Vincenza Conteduca,Sheng-Yu Ku,Loredana Puca,Megan Slade,Luisa Fernandez,Judy Hess,Rohan Bareja,Panagiotis J. Vlachostergios,Michael Sigouros,Juan Miguel Mosquera,Andrea Sboner,David M. Nanus,Olivier Elemento,Ryan Dittamore,Scott T. Tagawa,Himisha Beltran,Himisha Beltran +16 more
TL;DR: The data suggest that SLFN11 expression might identify patients with CRPC with a better response to platinum chemotherapy independent of histology or other genomic alterations.
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IMGT/PhyloGene: an on-line tool for comparative analysis of immunoglobulin and T cell receptor genes.
TL;DR: IMGT/PhyloGene is the first tool to use the IMGT expertized and standardized data for automated comparative analyses, and the first on-line software package for phylogenetic reconstruction to be integrated to a sequence database.
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An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer
Evanguelos Xylinas,Evanguelos Xylinas,Melanie R. Hassler,Dazhong Zhuang,Martin Krzywinski,Zeynep Erdem,Brian D. Robinson,Olivier Elemento,Thomas Clozel,Shahrokh F. Shariat +9 more
TL;DR: The data suggest that HOXA9 promoter methylation could serve as potential predictive biomarker and decitabine might sensitize resistant tumors in patients receiving cisplatin-based chemotherapy.
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The role of machine learning in clinical research: transforming the future of evidence generation
E. Hope Weissler,E. Hope Weissler,Tristan Naumann,Tomas Andersson,Rajesh Ranganath,Olivier Elemento,Yuan Luo,Daniel F. Freitag,James Benoit,Michael C. Hughes,Faisal Khan,Paul Slater,Khader Shameer,Matthew T. Roe,Emmette Hutchison,Scott H. Kollins,Uli C. Broedl,Zhaoling Meng,Jennifer L. Wong,Lesley H. Curtis,Erich Huang,Marzyeh Ghassemi +21 more
TL;DR: In this paper, the authors present the proceedings of a multi-stakeholder conference to discuss the current and future state of ML for clinical research, focusing on the operational and philosophical barriers to ML in clinical research.
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An atlas of substrate specificities for the human serine/threonine kinome
Jared L. Johnson,Tomer M. Yaron,Emily M. Huntsman,Alexander Kerelsky,Junho Song,Amit Regev,Ting Lin,Katarina M. Liberatore,Daniel M. Cizin,Benjamin M. Cohen,Neil Vasan,Yi Hua Ma,Konstantin Krismer,Jaylissa Torres Robles,B. van de Kooij,Anne van Vlimmeren,Nicole Andrée-Busch,Norbert F. Käufer,Maxim V. Dorovkov,Alexey G. Ryazanov,Yuichiro Takagi,Edward R. Kastenhuber,Marcus D. Goncalves,Benjamin D. Hopkins,Olivier Elemento,Dylan J. Taatjes,Alexandre Maucuer,Akio Yamashita,Alexei Degterev,Mohamed Saleem Thattakudian Sheik Uduman,Jingyi Lu,Sean D. Landry,Bin Zhang,Ian Cossentino,Rune Linding,John Blenis,Peter Hornbeck,Benjamin E. Turk,Michael B. Yaffe,Lewis C. Cantley +39 more
TL;DR: This article used synthetic peptide libraries to profile the substrate sequence specificity of 303 protein serine/threonine (Ser/Thr) kinases, comprising more than 84% of those predicted to be active in humans.