Olivier Elemento

TL;DR: In this paper , the authors applied advanced functional genomics to interrogate 9,000 human tumors and multiple single-cell sequencing sets using benchmarked T cell states, comprehensive T cell differentiation trajectories, human and mouse vaccine responses, and other human TILs.

TL;DR: In this paper , the authors developed an approach called UTAG to identify and quantify microanatomical tissue structures in multiplexed images without human intervention, which combines information on cellular phenotypes with the physical proximity of cells to accurately identify organ-specific microANATomical domains in healthy and diseased tissue.

TL;DR: The distinct distribution of TNBC subtypes and altered oncologic pathways show that the ethnic variations in TNBCs are driven by shared genetic ancestry, and tumors from patients of various ancestral origins should be evaluated.

TL;DR: Extent of UCHL1 IHC staining should be explored as a potentially clinically useful adjunct to Ki-67 index in evaluating GEP-NETs for aggressive features.