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Patrick S. G. Chain

Researcher at Los Alamos National Laboratory

Publications -  321
Citations -  38829

Patrick S. G. Chain is an academic researcher from Los Alamos National Laboratory. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 65, co-authored 301 publications receiving 34601 citations. Previous affiliations of Patrick S. G. Chain include McMaster University & Joint Genome Institute.

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Journal ArticleDOI

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower, +253 more
- 14 Jun 2012 - 
TL;DR: The Human Microbiome Project Consortium reported the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome as discussed by the authors.
Journal Article

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower, +247 more
- 01 Jun 2012 - 
TL;DR: The Human Microbiome Project has analysed the largest cohort and set of distinct, clinically relevant body habitats so far, finding the diversity and abundance of each habitat’s signature microbes to vary widely even among healthy subjects, with strong niche specialization both within and among individuals.
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A framework for human microbiome research

Barbara A. Methé, +253 more
- 14 Jun 2012 - 
TL;DR: The Human Microbiome Project (HMP) Consortium has established a population-scale framework which catalyzed significant development of metagenomic protocols resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomics data available to the scientific community as mentioned in this paper.
Journal ArticleDOI

The composite genome of the legume symbiont Sinorhizobium meliloti.

TL;DR: The annotated DNA sequence of the α-proteobacteriumSinorhizobium meliloti, the symbiont of alfalfa, is presented, indicating that all three elements contribute, in varying degrees, to symbiosis and reveals how this genome may have emerged during evolution.