P
Philip C. Calder
Researcher at University of Southampton
Publications - 808
Citations - 70822
Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers.
TL;DR: It is indicated that STA may be used as a precursor to increase the EPA content of human lipids and that combinations of GLA, STA and EPA can be used to manipulate the fatty acid compositions of lipid pools in subtle ways.
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The effects of conjugated linoleic acid on human health-related outcomes.
TL;DR: The consensus from seventeen published studies in human subjects is that CLA does not affect body weight or body composition, and there have been reports of some interesting isomer-specific effects of CLA on the blood lipid profile, but not on immune function.
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Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations.
Elizabeth A. Miles,Dinka Rees,Tapati Banerjee,Roberta Cazzola,Sian Lewis,Richard Wood,Rachael Oates,Anna Tallant,Benvenuto Cestaro,Parveen Yaqoob,K. W. Wahle,Philip C. Calder +11 more
TL;DR: Plasma concentrations of some inflammatory markers are positively correlated with age, independent of other cardiovascular risk factors, which suggests that age-related inflammation may not be driven by recognised risk factors.
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Lack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50–65 years consuming their habitual diets
TL;DR: It is suggested that differences in meal fatty acid composition exert little or no effect on postprandial changes in plasma lipids, glucose and insulin concentrations.
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Supplementation with N-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells.
Samuel P. Hoile,Rebecca Clarke-Harris,Rae-Chi Huang,Philip C. Calder,Trevor A. Mori,Lawrence J. Beilin,Karen A. Lillycrop,Graham C. Burdge +7 more
TL;DR: Findings show that modest fatty acid supplementation can induce altered methylation of specific CpG loci in adult humans, contingent on the nature of the supplement and on sex.