P
Philip C. Calder
Researcher at University of Southampton
Publications - 808
Citations - 70822
Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Reduced intestinal FADS1 gene expression and plasma omega-3 fatty acids following Roux-en-Y gastric bypass.
Priscila Garla,Priscila Sala,Raquel Susana Torrinhas,N.M. Machado,Danielle Cristina Fonseca,Mariane Marques da Silva,Graziela Rosa Ravacci,G. Belarmino,Robson Kiyoshi Ishida,Ismael Francisco Mota Siqueira Guarda,Eduardo Guimarães Hourneaux de Moura,Paulo Sakai,Marco Aurelio Santo,Ismael Dale Cotrim Guerreiro da Silva,Claudia Cristina Alves Pereira,Steven B. Heymsfield,Maria Lúcia Corrêa-Giannella,Philip C. Calder,Dan Linetzky Waitzberg +18 more
TL;DR: RYGB decreased PUFA ingestion, plasma ALA and EPA levels, and intestinal expression of FADS1 gene, the latter encodes a key enzyme involved in endogenous biosynthesis of PUFAs, suggest that supplementation of omega-3PUFAs may be required for obese patients undergoing RYGB.
Book ChapterDOI
The scientific basis for fish oil supplementation in rheumatoid arthritis
TL;DR: The amount and types of fat in the human diet, the components of the immune system and how they function to protect the host from infectious agents, and the immune dysfunction which occurs in rheumatoid arthritis are described.
Journal ArticleDOI
The ratio of n-6 to n-3 fatty acids in the diet: impact on T lymphocyte function
TL;DR: Les effets des acides gras polyinsatures n-3 and n-6 sur la multiplication des lymphocytes T, sur the production des cytokines par le lymphocyte T, la presentation de l'antigene et l'immunite cellulaire in vivo chez l'animal and l'homme ont ete etudies dans cet article de synthese.
Journal ArticleDOI
Intravenous omega-3 fatty acids are associated with better clinical outcome and less inflammation in patients with predicted severe acute pancreatitis: A randomised double blind controlled trial.
D. Al-Leswas,A. Eltweri,Wen Yuan Chung,A. Arshad,J.A. Stephenson,O. Al-Taan,C. Pollard,Helena L. Fisk,Philip C. Calder,G Garcea,M. Metcalfe,Ashley R. Dennison +11 more
TL;DR: It is concluded that intravenous administration of a fish oil containing lipid emulsion, a source of omega-3 FA, improves clinical outcomes in patients with predicted SAP, benefits that may be linked to reduced inflammation.
Journal ArticleDOI
Different dietary omega-3 sources during pregnancy and DHA in the developing rat brain
TL;DR: It was observed that pups from dams feeding the ALA rich diet had a comparable brain DHA status to those from dams fed on a salmon-oil based diet, indicating that conversion of ALA to DHA during pregnancy was efficient, and that DHA accumulated in a tissue-specific manner.