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Philip C. Calder

Researcher at University of Southampton

Publications -  808
Citations -  70822

Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.

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Relation between the fatty acid composition of peripheral blood mononuclear cells and measures of immune cell function in healthy, free-living subjects aged 25–72 y

TL;DR: Variations in the fatty acid composition of PBMC phospholipids account for some of the variability in immune cell functions among healthy adults.
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Is there a role for fatty acids in early life programming of the immune system

TL;DR: Fish oil supplementation in infancy may decrease the risk of developing some manifestations of allergic disease, but whether this benefit persists as other factors come into play remains to be determined.
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Immunonutrition in surgical and critically ill patients

TL;DR: Experimental studies support a role for several amino acids, antioxidant vitamins and minerals, long-chain n-3 fatty acids and nucleotides in surgical, injured or critically ill patients and good evidence that glutamine influences immune function in such patients and that this is associated with clinical improvement.
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Monitoring immune modulation by nutrition in the general population: identifying and substantiating effects on human health.

TL;DR: A stepwise approach offers a clear rationale for selecting markers for future trials and provides a framework for the interpretation of outcomes, and may also be useful to rationalise the selection and interpretation of markers for other physiological processes critical to the maintenance of health and well-being.
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Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids

TL;DR: Results from these studies indicate that fish oil feeding reduces rat liver apolipoproteins A-I and apo A-II gene expression, similar to results obtained after feeding fenofibrate.