P
Philip C. Calder
Researcher at University of Southampton
Publications - 808
Citations - 70822
Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Dietary lipids modify the cytokine response to bacterial lipopolysaccharide in mice
TL;DR: The enhanced production of IL‐10 following CO feeding appears to be an additional antiinflammatory effect of this oil, which could give added benefit in various clinical conditions.
Journal ArticleDOI
Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12® and Lactobacillus paracasei ssp. paracasei, L. casei 431® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study.
Giuliano Rizzardini,Dorte Eskesen,Philip C. Calder,Amedeo Capetti,Lillian Jespersen,Mario Clerici +5 more
TL;DR: Data herein show that supplementation with BB-12® or L. casei 431 may be an effective means to improve immune function by augmenting systemic and mucosal immune responses to challenge.
Journal ArticleDOI
Effect of olive oil on immune function in middle-aged men.
Parveen Yaqoob,J. A. Knapper,D. H Webb,Christine M. Williams,Eric A. Newsholme,Philip C. Calder +5 more
TL;DR: There was a significant decrease in the expression of intercellular adhesion molecule 1 by peripheral blood mononuclear cells from subjects consuming the MUFA diet, which may have implications for the influence of dietary fat on inflammatory diseases, including atherosclerosis.
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Polyunsaturated fatty acids and rheumatoid arthritis.
TL;DR: A number of double-blind, placebo-controlled trials of γ-linolenic acid and fish oil in rheumatoid arthritis have shown significant improvements in a variety of clinical outcomes, but it is unclear what the optimal dosage of the fatty acids is, or whether there would be extra benefit from using them in combination.
Journal ArticleDOI
Long-chain n-3 fatty acids and inflammation: potential application in surgical and trauma patients
TL;DR: Clinical studies performed in various patient groups have indicated benefit from the use of fish oil, which contains long chain n-3 fatty acids, such as eicosapentaenoic acid, which can potentially reduce platelet aggregation, blood clotting, smooth muscle contraction, and leukocyte chemotaxis.