P
Philip C. Calder
Researcher at University of Southampton
Publications - 808
Citations - 70822
Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis.
TL;DR: The results suggest that membrane fluidity is important in determining macrophage adhesion and phagocytic activity, and may be possible to modulate the activity of cells of the immune system, and so an immune response, by dietary lipid manipulation.
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Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans
Sabine Tricon,Graham C. Burdge,Samantha Kew,Tapati Banerjee,Jennifer J. Russell,Emma L Jones,Robert F. Grimble,Christine M. Williams,Parveen Yaqoob,Philip C. Calder +9 more
TL;DR: Divergent effects of cis-9,trans-11 CLA and trans-10,cis-12 CLA appear on the blood lipid profile in healthy humans: trans-8,9,9 CLA increases LDL:HDL cholesterol and total: HDL cholesterol, whereas cis-7,8,8 CLA decreases them.
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Markers to measure immunomodulation in human nutrition intervention studies
Ruud Albers,Jean-Michel Antoine,Raphaëlle Bourdet-Sicard,Philip C. Calder,Michael Gleeson,Bruno Lesourd,Sonia Samartín,Ian R. Sanderson,Jan Van Loo,F. Willem Vas Dias,Bernhard Watzl +10 more
TL;DR: It would be valuable to include several immune markers in addition to clinical outcome in future clinical trials in this area, as there is too little evidence that correlates markers with global health improvement.
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Nutrition, immunity and COVID-19.
TL;DR: It would seem prudent for individuals to consume sufficient amounts of essential nutrients to support their immune system to help them deal with pathogens should they become infected.
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Metabolism and functional effects of plant-derived omega-3 fatty acids in humans
Ella J. Baker,Elizabeth A. Miles,Graham C. Burdge,Parveen Yaqoob,Philip C. Calder,Philip C. Calder +5 more
TL;DR: If conversion of ALA to EPA and DHA is limited, then ALA may have a smaller health benefit than EPA andDHA, and SDA appears to offer better potential for health improvement than ALA.