P
Philip C. Calder
Researcher at University of Southampton
Publications - 808
Citations - 70822
Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
The immune system: a target for functional foods?
Philip C. Calder,Samantha Kew +1 more
TL;DR: It is not clear how the variation in immune function among healthy individuals relates to variation in susceptibility to infection, and there is increasing evidence that probiotic bacteria improve host immune function.
Journal ArticleDOI
Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis.
TL;DR: Evidence is seen for a fairly consistent, but modest, benefit of marine n-3 PUFAs on joint swelling and pain, duration of morning stiffness, global assessments of pain and disease activity, and use of non-steroidal anti-inflammatory drugs.
Journal ArticleDOI
Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease.
TL;DR: Strong evidence indicates n-3 PUFAs are beneficial as a dietary supplement in certain diseases such as rheumatoid arthritis; however for other conditions such as asthma, the data are less robust.
Journal ArticleDOI
n-3 Polyunsaturated fatty acids and cytokine production in health and disease
TL;DR: Animal studies indicate that dietary fish oil reduces the response to endotoxin and to pro-inflammatory cytokines, resulting in increased survival; such diets have been beneficial in some models of bacterial challenge, chronic inflammation and auto-immunity.
Journal ArticleDOI
PASSCLAIM - gut health and immunity
John H. Cummings,Jean-Michel Antoine,Fernando Azpiroz,Raphaëlle Bourdet-Sicard,Per Brandtzaeg,Philip C. Calder,Glenn R. Gibson,Francisco Guarner,Erika Isolauri,Daphne Pannemans,Colette Shortt,Sandra Tuijtelaars,Bernhard Watzl +12 more
TL;DR: To define normal function of the gut and immune system and describe available methods of measuring it, the digestive tract is most frequently the object of functional and health claims and a large market already exists for gut-functional foods worldwide.