P
Philip C. Calder
Researcher at University of Southampton
Publications - 808
Citations - 70822
Philip C. Calder is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 125, co-authored 747 publications receiving 59110 citations. Previous affiliations of Philip C. Calder include Southampton General Hospital & Radboud University Nijmegen Medical Centre.
Papers
More filters
Journal ArticleDOI
Inhibition of tumour necrosis factor-alpha and interleukin 6 production by mononuclear cells following dietary fish-oil supplementation in healthy men and response to antioxidant co-supplementation.
Timothy M Trebble,Nigel K Arden,Mike Stroud,Stephen A. Wootton,Graham C. Burdge,Elizabeth A. Miles,Anne B. Ballinger,Rachel Thompson,Philip C. Calder +8 more
TL;DR: There was a positive dose-dependent relationship between dietary n-3 PUFA intake and EPA and DHA incorporation into plasma phosphatidylcholine and erythrocyte phosph atidylethanolamine, with a tendency towards a plateau at higher levels of intake.
Journal ArticleDOI
Early nutrition and immunity – progress and perspectives
Philip C. Calder,Susanne Krauss-Etschmann,Esther C. de Jong,Christophe Dupont,Julia-Stefanie Frick,Hanne Frøkiær,Joachim Heinrich,Holger Garn,Sibylle Koletzko,Gideon Lack,Gianluca Mattelio,Harald Renz,Per T. Sangild,Jürgen Schrezenmeir,Thomas M. Stulnig,Thomas Thymann,Agnes E. Wold,Berthold Koletzko +17 more
TL;DR: The development of tolerance is the result of active immune mechanisms and both development and maintenance of tolerance are lifelong processes which start very early in life, even prenatally as mentioned in this paper, and a breakdown in the tolerogenic pathways can also lead to inflammatory diseases.
Journal ArticleDOI
The impact of long-chain n-3 polyunsaturated fatty acids on human health
TL;DR: Although intervention trials in rheumatoid arthritis show strong evidence of benefit, evidence for efficacy in other inflammatory conditions, including Crohn's disease, ulcerative colitis, psoriasis, lupus, multiple sclerosis, cystic fibrosis and asthma is inconsistent or inadequate.
Journal ArticleDOI
Glutamine and the immune system
Philip C. Calder,Parveen Yaqoob +1 more
TL;DR: The provision of glutamine or its precursors to patients following bone marrow transplantation resulted in a lower level of infection and a shorter stay in hospital than for patients receiving glutamine-free parenteral nutrition.
Journal ArticleDOI
The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability.
TL;DR: The anti-inflammatory effects of marine n-3 polyunsaturated fatty acids (PUFAs) may contribute to their protective actions towards atherosclerosis and plaque rupture.