Chung-Ang University

About: Chung-Ang University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Thin film. The organization has 13381 authors who have published 26978 publications receiving 416735 citations. The organization is also known as: CAU & Chung.

Understanding the Model Size Effect on SEM Fit Indices

Abstract: This study investigated the effect the number of observed variables (p) has on three structural equation modeling indices: the comparative fit index (CFI), the Tucker-Lewis index (TLI), and the root mean square error of approximation (RMSEA). The behaviors of the population fit indices and their sample estimates were compared under various conditions created by manipulating the number of observed variables, the types of model misspecification, the sample size, and the magnitude of factor loadings. The results showed that the effect of p on the population CFI and TLI depended on the type of specification error, whereas a higher p was associated with lower values of the population RMSEA regardless of the type of model misspecification. In finite samples, all three fit indices tended to yield estimates that suggested a worse fit than their population counterparts, which was more pronounced with a smaller sample size, higher p, and lower factor loading.

Evidence for a Field-Induced Quantum Spin Liquid in α - RuCl 3

Abstract: We report a $^{35}\mathrm{Cl}$ nuclear magnetic resonance study in the honeycomb lattice $\ensuremath{\alpha}$-${\mathrm{RuCl}}_{3}$, a material that has been suggested to potentially realize a Kitaev quantum spin liquid (QSL) ground state. Our results provide direct evidence that $\ensuremath{\alpha}$-${\mathrm{RuCl}}_{3}$ exhibits a magnetic-field-induced QSL. For fields larger than $\ensuremath{\sim}10\text{ }\text{ }\mathrm{T}$, a spin gap opens up while resonance lines remain sharp, evidencing that spins are quantum disordered and locally fluctuating. The spin gap increases linearly with an increasing magnetic field, reaching $\ensuremath{\sim}50\text{ }\text{ }\mathrm{K}$ at 15 T, and is nearly isotropic with respect to the field direction. The unusual rapid increase of the spin gap with increasing field and its isotropic nature are incompatible with conventional magnetic ordering and, in particular, exclude that the ground state is a fully polarized ferromagnet. The presence of such a field-induced gapped QSL phase has indeed been predicted in the Kitaev model.

Human astrocytes: secretome profiles of cytokines and chemokines.

Abstract: Astrocytes play a key role in maintenance of neuronal functions in the central nervous system by producing various cytokines, chemokines, and growth factors, which act as a molecular coordinator of neuron-glia communication. At the site of neuroinflammation, astrocyte-derived cytokines and chemokines play both neuroprotective and neurotoxic roles in brain lesions of human neurological diseases. At present, the comprehensive profile of human astrocyte-derived cytokines and chemokines during inflammation remains to be fully characterized. We investigated the cytokine secretome profile of highly purified human astrocytes by using a protein microarray. Non-stimulated human astrocytes in culture expressed eight cytokines, including G-CSF, GM-CSF, GROα (CXCL1), IL-6, IL-8 (CXCL8), MCP-1 (CCL2), MIF and Serpin E1. Following stimulation with IL-1β and TNF-α, activated astrocytes newly produced IL-1β, IL-1ra, TNF-α, IP-10 (CXCL10), MIP-1α (CCL3) and RANTES (CCL5), in addition to the induction of sICAM-1 and complement component 5. Database search indicated that most of cytokines and chemokines produced by non-stimulated and activated astrocytes are direct targets of the transcription factor NF-kB. These results indicated that cultured human astrocytes express a distinct set of NF-kB-target cytokines and chemokines in resting and activated conditions, suggesting that the NF-kB signaling pathway differentially regulates gene expression of cytokines and chemokines in human astrocytes under physiological and inflammatory conditions.