Institution
Indian Institute of Technology Bombay
Education•Mumbai, India•
About: Indian Institute of Technology Bombay is a education organization based out in Mumbai, India. It is known for research contribution in the topics: Catalysis & Computer science. The organization has 16756 authors who have published 33588 publications receiving 570559 citations.
Topics: Catalysis, Computer science, Thin film, Population, Heat transfer
Papers published on a yearly basis
Papers
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TL;DR: This review highlights the various strategies employed for the preparation of trigger responsive polymeric nanocarriers for cancer therapy and provides an overview of the state of the art in this field.
Abstract: Conventional chemotherapy for the treatment of cancer has limited specificity when administered systemically and is often associated with toxicity issues. Enhanced accumulation of polymeric nanocarriers at a tumor site may be achieved by passive and active targeting. Incorporation of trigger responsiveness into these polymeric nanocarriers improves the anticancer efficacy of such systems by modulating the release of the drug according to the tumor environment. Triggers used for tumor targeting include internal triggers such as pH, redox and enzymes and external triggers such as temperature, magnetic field, ultrasound and light. While internal triggers are specific cues of the tumor microenvironment, external triggers are those which are applied externally to control the release. This review highlights the various strategies employed for the preparation of such trigger responsive polymeric nanocarriers for cancer therapy and provides an overview of the state of the art in this field.
114 citations
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TL;DR: In this paper, the elastic buckling of skew fiber-reinforced composite and sandwich plates subjected to thermal loads is considered and two shear deformable finite element models are employed to obtain thermal buckling solutions.
114 citations
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TL;DR: A biphasic suspension of the dendrimer–drug conjugate and a magnetic fluid entitles release of the drug under AC magnetic field which can simultaneously be used for hyperthermia treatment of cancer.
Abstract: An oligo(ethylene glycol)- grafted amidoamine dendrimer was synthesized and characterized by FTIR, MS, 1H and 13C NMR. The dendritic scaffold was evaluated for its potential to load doxorubicin and its release, thereafter. The interaction between drug and the dendrimer was reviewed by ζ potential, HPLC, NMR and FTIR spectroscopy. The drug encapsulation efficiency was as high as 52%. The temperature stimulated release characteristics of the DOX loaded dendrimers were studied in PBS and SBF at 37 °C (physiological temperature) and 43 °C (hyperthermic temperature). A biphasic suspension of the dendrimer–drug conjugate and a magnetic fluid entitles release of the drug under AC magnetic field which can simultaneously be used for hyperthermia treatment of cancer. The efficacy of dendrimer–DOX conjugate was evaluated in vitro against cancer cell lines and the IC50 was estimated.
114 citations
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TL;DR: In this paper, the effect of excitation frequency on the synthetic jet flow is studied for cavities of different depths and for orifices of different diameters, and the results are expected to be useful for designing synthetic jet cavity.
113 citations
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TL;DR: In this paper, a review on the influences of various factors on the moisture susceptibility of WMA mixtures is presented, where the influence of materials and technologies are illustrated, including aggregate, asphalt, compacting temperature and other warm mix technologies.
113 citations
Authors
Showing all 17055 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jovan Milosevic | 152 | 1433 | 106802 |
C. N. R. Rao | 133 | 1646 | 86718 |
Robert R. Edelman | 119 | 605 | 49475 |
Claude Andre Pruneau | 114 | 610 | 45500 |
Sanjeev Kumar | 113 | 1325 | 54386 |
Basanta Kumar Nandi | 112 | 572 | 43331 |
Shaji Kumar | 111 | 1265 | 53237 |
Josep M. Guerrero | 110 | 1197 | 60890 |
R. Varma | 109 | 497 | 41970 |
Vijay P. Singh | 106 | 1699 | 55831 |
Vinayak P. Dravid | 103 | 817 | 43612 |
Swagata Mukherjee | 101 | 1048 | 46234 |
Anil Kumar | 99 | 2124 | 64825 |
Dhiman Chakraborty | 96 | 529 | 44459 |
Michael D. Ward | 95 | 823 | 36892 |