Institution
Indian Institute of Technology Indore
Education•Indore, Madhya Pradesh, India•
About: Indian Institute of Technology Indore is a education organization based out in Indore, Madhya Pradesh, India. It is known for research contribution in the topics: Computer science & Chemistry. The organization has 1606 authors who have published 4803 publications receiving 66500 citations.
Topics: Computer science, Chemistry, Catalysis, Fading, Raman spectroscopy
Papers published on a yearly basis
Papers
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TL;DR: In this article, the impact of regression algorithms on prediction accuracy in the brain age estimation frameworks have not been comprehensively evaluated; however, they have shown that regression algorithms can lead to more accurate brain age predictions in clinical settings.
Abstract: Machine learning (ML) algorithms play a vital role in brain age estimation frameworks. The impact of regression algorithms on prediction accuracy in the brain age estimation frameworks have not been comprehensively evaluated. Here, we sought to assess the efficiency of different regression algorithms on brain age estimation. To this end, we built a brain age estimation framework based on a large set of cognitively healthy (CH) individuals (N = 788) as a training set followed by different regression algorithms (18 different algorithms in total). We then quantified each regression-algorithm on independent test sets composed of 88 CH individuals, 70 mild cognitive impairment patients as well as 30 Alzheimers disease patients. The prediction accuracy in the independent test set (i.e., CH set) varied in regression algorithms (mean absolute error (MAE) from 4.63 to 7.14 yrs, R2 from 0.76 to 0.88). The highest and lowest prediction accuracies were achieved by Quadratic Support Vector Regression algorithm (MAE = 4.63 yrs, R2 = 0.88, 95% CI = [-1.26, 1.42]) and Binary Decision Tree algorithm (MAE = 7.14 yrs, R2 = 0.76, 95% CI = [-1.50, 2.62]), respectively. Our experimental results demonstrate that prediction accuracy in brain age frameworks is affected by regression algorithms, indicating that advanced machine learning algorithms can lead to more accurate brain age predictions in clinical settings.
32 citations
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TL;DR: In this paper, a novel water-stable luminescent terbium metal-organic framework, Tb(L1)(L2)0.5(NO3)(DMF)]·DMF, with 1,10-phenanthroline (phen) and 3,3′,5,5′-azobenzene-tetracarboxylic acid (H4abtc) ligands was solvothermally synthesized and structurally characterized.
Abstract: Herein, a novel water-stable luminescent terbium metal–organic framework, {[Tb(L1)(L2)0.5(NO3)(DMF)]·DMF}n (TPA-MOF), with 1,10-phenanthroline (phen) and 3,3′,5,5′-azobenzene-tetracarboxylic acid (H4abtc) ligands was solvothermally synthesized and structurally characterized. TPA-MOF possesses a two-dimensional (2D) extended framework featuring an 8-connected uninodal SP2-periodic net topology with the Schlafli point symbol of {3^12;4^14;5^2}. The π-electron rich luminescent TPA-MOF exhibits four characteristic emission bands of Tb3+ ion and acts as a selective and sensitive probe for acetone as well as the electron deficient 2,4,6-trinitrophenol (TNP). Moreover, gas sorption studies confirm that TPA-MOF displays ultra-micropores and adsorbs moderate amounts of N2 and CO2.
32 citations
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TL;DR: In this article, a theoretical model is proposed to study the fluid flow and heat transfer behavior of two-dimensional impinging jets on a solid surface, and a generalized expression involving various modelling parameters such as Nusselt number, nozzle to plate distance, Prandtl number, Reynolds number and the modelling parameter k is obtained.
32 citations
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TL;DR: TPV was found to be the most potent against subtype D due to an increase in van der Waals and electrostatic interactions and reduction in the desolvation energy compared to other inhibitors, and this result is further supported by the hydrogen bond interactions between inhibitors and protease.
Abstract: Acquired immune deficiency syndrome (AIDS) is caused by the human immunodeficiency virus (HIV), type 1 and 2. Further, the diversity in HIV-1 has given rise to many serotypes and recombinant strain...
32 citations
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Imperial College London1, I.M. Sechenov First Moscow State Medical University2, University of Hertfordshire3, Huazhong University of Science and Technology4, University of Bologna5, Indian Institute of Technology Indore6, N. I. Lobachevsky State University of Nizhny Novgorod7, King Juan Carlos University8, University of Aberdeen9, University College London10
TL;DR: This review considers how recent progression in mathematical modeling can be utilized to investigate aging, particularly in, but not exclusive to, the context of degenerative neuronal disease and how the latest techniques for generating biomarker models for disease prediction can be applied to as both biomarker platforms for aging.
Abstract: Biological aging is a complex process involving multiple biological processes. These can be understood theoretically though considering them as individual networks-e.g., epigenetic networks, cell-cell networks (such as astroglial networks), and population genetics. Mathematical modeling allows the combination of such networks so that they may be studied in unison, to better understand how the so-called "seven pillars of aging" combine and to generate hypothesis for treating aging as a condition at relatively early biological ages. In this review, we consider how recent progression in mathematical modeling can be utilized to investigate aging, particularly in, but not exclusive to, the context of degenerative neuronal disease. We also consider how the latest techniques for generating biomarker models for disease prediction, such as longitudinal analysis and parenclitic analysis can be applied to as both biomarker platforms for aging, as well as to better understand the inescapable condition. This review is written by a highly diverse and multi-disciplinary team of scientists from across the globe and calls for greater collaboration between diverse fields of research.
31 citations
Authors
Showing all 1738 results
Name | H-index | Papers | Citations |
---|---|---|---|
Raghunath Sahoo | 106 | 556 | 37588 |
Biswajeet Pradhan | 98 | 735 | 32900 |
A. Kumar | 96 | 505 | 33973 |
Franco Meddi | 84 | 476 | 24084 |
Manish Sharma | 82 | 1407 | 33361 |
Anindya Roy | 59 | 301 | 14306 |
Krishna R. Reddy | 58 | 400 | 11076 |
Sudipan De | 54 | 99 | 10774 |
Sudip Chakraborty | 51 | 343 | 9319 |
Shaikh M. Mobin | 51 | 515 | 11467 |
Ashok Kumar | 50 | 405 | 10001 |
Ankhi Roy | 49 | 259 | 8634 |
Aditya Nath Mishra | 49 | 139 | 7607 |
Ram Bilas Pachori | 48 | 182 | 8140 |
Pragati Sahoo | 47 | 133 | 6535 |