Institution
Jawaharlal Nehru University
Education•New Delhi, India•
About: Jawaharlal Nehru University is a education organization based out in New Delhi, India. It is known for research contribution in the topics: Population & Politics. The organization has 6082 authors who have published 13455 publications receiving 245407 citations. The organization is also known as: JNU.
Topics: Population, Politics, Gene, Candida albicans, Computer science
Papers published on a yearly basis
Papers
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TL;DR: The latest knowledge is brought out about the structure and functions of histidine kinases in cytokinin and ethylene signaling and their role(s) in development and the regulation of environmental stress responses.
Abstract: Two-component signaling pathways involve sensory histidine kinases (HK), histidine phosphotransfer proteins (HpT) and response regulators (RR). Recent advancements in genome sequencing projects for a number of plant species have established the TCS family to be multigenic one. In plants, HKs operate through the His-Asp phosphorelay and control many physiological and developmental processes throughout the lifecycle of plants. Despite the huge diversity reported for the structural features of the HKs, their functional redundancy has also been reported via mutant approach. Several sensory HKs having a CHASE domain, transmembrane domain(s), transmitter domain and receiver domain have been reported to be involved in cytokinin and ethylene signaling. On the other hand, there are also increasing evidences for some of the sensory HKs to be performing their role as osmosensor, clearly indicating toward a possible cross-talk between hormone and stress responsive cascades. In this review, we bring out the latest knowledge about the structure and functions of histidine kinases in cytokinin and ethylene signaling and their role(s) in development and the regulation of environmental stress responses.
85 citations
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TL;DR: The rational and the high throughput strategies that can be used for the construction of such improved host cell platforms for recombinant protein expression is the focus of this review.
Abstract: A metabolic engineering perspective which views recombinant protein expression as a multistep pathway allows us to move beyond vector design and identify the downstream rate limiting steps in expression. In E.coli these are typically at the translational level and the supply of precursors in the form of energy, amino acids and nucleotides. Further recombinant protein production triggers a global cellular stress response which feedback inhibits both growth and product formation. Countering this requires a system level analysis followed by a rational host cell engineering to sustain expression for longer time periods. Another strategy to increase protein yields could be to divert the metabolic flux away from biomass formation and towards recombinant protein production. This would require a growth stoppage mechanism which does not affect the metabolic activity of the cell or the transcriptional or translational efficiencies. Finally cells have to be designed for efficient export to prevent buildup of proteins inside the cytoplasm and also simplify downstream processing. The rational and the high throughput strategies that can be used for the construction of such improved host cell platforms for recombinant protein expression is the focus of this review.
85 citations
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TL;DR: In this paper, the authors explored the potential effects of driving factors on COVID-19 counts in the contiguous United States and found that ethnicity, crime, and income factors are the strongest covariates and explain most of the variance of the modeling estimation.
85 citations
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01 Aug 2012TL;DR: The authors recuperates the links between imperialism and primitive accumulation, arguing that the two are inherently connected and undertakes a review of the literature to show that the links are deeper than is often recognized, as in the work of David Harvey.
Abstract: This article recuperates the links between imperialism and primitive accumulation, arguing that the two are inherently connected. It undertakes a review of the literature to show that the links are deeper than is often recognized, as in the work of David Harvey. It also maps the stages of imperialism, their logics and characteristics, from the initial expansion of merchant capitalism, through monopoly capitalism and its financialization, which is now leading a ‘new scramble’. The article shows how the various scrambles for Africa have evolved, including past and present land grabs, as well as the nature of resistance.
85 citations
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TL;DR: The gender difference in HCE in short-term and major morbidity in India is examined, and the role of factors underlying the difference is understood to understand the contribution of demographic and socio-economic factors.
Abstract: Background
While the gender disparity in health and mortality in various stages of life in India is well documented, there is limited evidence on female disadvantage in health-care expenditure (HCE).
85 citations
Authors
Showing all 6255 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ashok Kumar | 151 | 5654 | 164086 |
Rajesh Kumar | 149 | 4439 | 140830 |
Sanjay Gupta | 99 | 902 | 35039 |
Rakesh Kumar | 91 | 1959 | 39017 |
Praveen Kumar | 88 | 1339 | 35718 |
Rajendra Prasad | 86 | 945 | 29526 |
Mukesh K. Jain | 85 | 539 | 27485 |
Shiv Kumar Sarin | 84 | 740 | 28368 |
Gaurav Sharma | 82 | 1244 | 31482 |
Santosh Kumar | 80 | 1196 | 29391 |
Dinesh Mohan | 79 | 283 | 35775 |
Govindjee | 76 | 426 | 21800 |
Dipak K. Das | 75 | 327 | 17708 |
Amit Verma | 70 | 497 | 16162 |
Manoj Kumar | 65 | 408 | 16838 |