Jawaharlal Nehru University

About: Jawaharlal Nehru University is a education organization based out in New Delhi, India. It is known for research contribution in the topics: Population & Politics. The organization has 6082 authors who have published 13455 publications receiving 245407 citations. The organization is also known as: JNU.

Engendering local democracy: The impact of quotas for women in India's panchayats

Abstract: In 1992, India's Parliament enacted two constitutional amendments that sought to democratize local governance and engender it through quota-based reservations for women. This article asks whether participation in these institutions has enabled women to articulate and advance their interests. To evaluate this, the article deploys the distinction in feminist literature between strategic and practical gender interests. Through a survey of a wide range of studies conducted in different parts of India it points to the constraints, both of institutional design as well as of social inequalities of gender and caste, that inhibit a fuller and more effective participation by women. There is nevertheless evidence to suggest that the quotas have enabled women to address their practical gender needs and interests, even if the articulation and realization of strategic interests is moving at a somewhat slower pace.

Antioxidant and Antimicrobial Properties of the Essential Oil and Extracts of Zanthoxylum alatum Grown in North-Western Himalaya

Abstract: The essential oil obtained from the fresh leaves of Zanthoxylum alatum was analysed by gas chromatography/mass spectrometry (GC/MS). Fourteen components were identified, and linalool (30.58%), 2-decanone (20.85%), β -fenchol (9.43%), 2-tridecanone (8.86%), β -phellandrene (5.99%), Sabinene (4.82%), and α -pinene (4.11%) were the main components. The EO and methanolic extract of Z. alatum exhibited potent antifungal activity against Alternaria alternata, Alternaria brassicae, and Curvularia lunata. The EO also showed significant antibacterial activity against Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus, and Escherichia coli. Further, antimicrobial constituents of the EO were isolated by bioautography and preparative thin layer chromatography (PTLC) and identified as β -fenchol and linalool using GC/MS analysis. In addition to this, the free radical scavenging activity and antioxidant potential of EO and methanolic extract/fractions of Z. alatum were also investigated using in vitro assays including scavenging ability against DPPH(•), reducing power and chelating ability on Fe(2+) ions. Our results demonstrate that Z. alatum could be used as a resource of antioxidant and antimicrobial compounds which may find applications in food and pesticide industries.

Quantitative modeling of groundwater in Satluj River basin of Rupnagar district of Punjab using remote sensing and geographic information system

Abstract: Water is a fluctuating resource making it difficult to measure in time and in space. To demonstrate the efficiency of the geographic information system (GIS) for groundwater studies, information on the parameters controlling groundwater such as lithology, geomorphology and lineament analysis were analyzed. LISS-III and Landsat satellite image of the area was used to infer information on the geologic lineaments and geomorphology. To delineate linear features enhancement and direction, filtering was performed on single bands of Landsat images. Thematic maps for geology, slope, geomorphology and lineament were prepared and integrated in GIS by assigning the weights and ranking to various parameters controlling the occurrence of groundwater to generate the groundwater potential map for the study area. The results indicate that the floodplain of river and its adjoining areas have very good groundwater potential, whereas the steeply sloping area in the northern part having high relief and slope possesses poor groundwater potential.

Profile of PAHs in the inhalable particulate fraction: source apportionment and associated health risks in a tropical megacity.

Abstract: The present study proposed to investigate the atmospheric distribution, sources, and inhalation health risks of polycyclic aromatic hydrocarbons (PAHs) in a tropical megacity (Delhi, India). To this end, 16 US EPA priority PAHs were measured in the inhalable fraction of atmospheric particles (PM10; aerodynamic diameter, ≤10 μm) collected weekly at three residential areas in Delhi from December 2008 to November 2009. Mean annual 24 h PM10 levels at the sites (166.5–192.3 μg m−3) were eight to ten times the WHO limit. Weekday/weekend effects on PM10 and associated PAHs were investigated. Σ16PAH concentrations (sum of 16 PAHs analyzed; overall annual mean, 105.3 ng m−3; overall range, 10.5–511.9 ng m−3) observed were at least an order of magnitude greater than values reported from European and US cities. Spatial variations in PAHs were influenced by nearness to traffic and thermal power plants while seasonal variation trends showed highest concentrations in winter. Associations between Σ16PAHs and various meteorological parameters were investigated. The overall PAH profile was dominated by combustion-derived large-ring species (85–87 %) that were essentially local in origin. Carcinogenic PAHs contributed 58–62 % to Σ16PAH loads at the sites. Molecular diagnostic ratios were used for preliminary assessment of PAH sources. Principal component analysis coupled with multiple linear regression-identified vehicular emissions as the predominant source (62–83 %), followed by coal combustion (18–19 %), residential fuel use (19 %), and industrial emissions (16 %). Spatio-temporal variations and time-evolution of source contributions were studied. Inhalation cancer risk assessment showed that a maximum of 39,780 excess cancer cases might occur due to lifetime inhalation exposure to the analyzed PAH concentrations.

Bio-distribution and toxicity assessment of intravenously injected anti-HER2 antibody conjugated CdSe/ZnS quantum dots in Wistar rats

Abstract: Anti-HER2 antibody conjugated with quantum dots (anti-HER2ab-QDs) is a very recent fluorescent nanoprobe for HER2+ve breast cancer imaging. In this study we investigated in-vivo toxicity of anti-HER2ab conjugated CdSe/ZnS QDs in Wistar rats. For toxicity evaluation of injected QDs sample, body weight, organ coefficient, complete blood count (CBC), biochemistry panel assay (AST, ALT, ALP, and GGTP), comet assay, reactive oxygen species, histology, and apoptosis were determined. Wistar rat (8–10 weeks old) were randomly divided into 4 treatment groups (n = 6). CBC and biochemistry panel assay showed nonsignificant changes in the anti-HER2ab-QDs treated group but these changes were significant (P < 0.05) in QDs treated group. No tissue damage, inflammation, lesions, and QDs deposition were found in histology and TEM images of the anti-HER2ab-QDs treated group. Apoptosis in liver and kidney was not found in the anti-HER2ab-QDs treated group. Animals treated with nonconjugated QDs showed comet formation and apoptosis. Cadmium deposition was confirmed in the QDs treated group compared with the anti-HER2ab-QDs treated group. The QDs concentration (500 nM) used for this study is suitable for in-vivo imaging. The combine data of this study support the biocompatibility of anti-HER2ab-QDs for breast cancer imaging, suggesting that the antibody coating assists in controlling any possible adverse effect of quantum dots.