Institution
Jawaharlal Nehru University
Education•New Delhi, India•
About: Jawaharlal Nehru University is a education organization based out in New Delhi, India. It is known for research contribution in the topics: Population & Politics. The organization has 6082 authors who have published 13455 publications receiving 245407 citations. The organization is also known as: JNU.
Topics: Population, Politics, Gene, Candida albicans, Computer science
Papers published on a yearly basis
Papers
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TL;DR: The introduction of molecular oxygen into the atmosphere was accompanied by the generation of reactive oxygen species (ROS) as side products of many biochemical reactions.
Abstract: The introduction of molecular oxygen into the atmosphere was accompanied by the generation of reactive oxygen species (ROS) as side products of many biochemical reactions. ROS are permanently generated in plastids, peroxisomes, mitochiondria, the cytosol and the apoplast. Imbalance between ROS generation and safe detoxification generates oxidative stress and the accumulating ROS are harmful for the plants. On the other hand, specific ROS function as signaling molecules and activate signal transduction processes in response to various stresses. Here, we summarize the generation of ROS in the different cellular compartments and the signaling processes which are induced by ROS.
497 citations
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TL;DR: The aim is to use Fourier techniques to analyse this periodicity, and thereby to develop a tool to recognize coding regions in genomic DNA, and find that the relative-height of the peak at f = 1/3 in the Fourier spectrum is a good discriminator of coding potential.
Abstract: Motivation: The major signal in coding regions of genomic sequences is a three-base periodicity. Our aim is to use Fourier techniques to analyse this periodicity, and thereby to develop a tool to recognize coding regions in genomic DNA. Result: The three-base periodicity in the nucleotide arrangement is evidenced as a sharp peak at frequency f — 1/3 in the Fourier (or power) spectrum. From extensive spectral analysis of DNA sequences of total length over 5.5 million base pairs from a wide variety or organisms (including the human genome), and by separately examining coding and non-coding sequences, we find that the relative height of the peak at f = 1/3 in the Fourier spectrum is a good discriminator of coding potential. This feature is utilized by us to detect probable coding regions in DNA sequences, by examining the local signal-to-noise ratio of the peak within a sliding window. While the overall accuracy is comparable to that of other techniques currently in use, the measure that is presently proposed is independent of training sets or existing database information, and can thus find general application. Availability: A computer program GeneScan which locates coding open reading frames and exonic regions in genomic sequences has been developed, and is available on request. Contact: E-mail: rama@jnuniv.emet.in.
469 citations
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TL;DR: It is shown that alpha-tocopherol plays an important role in the alleviation of stress induced by salt, heavy metal and osmoticum in Brassica juncea.
461 citations
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TL;DR: Out of the almost 17 members of the TNF superfamily, TNF is probably the most potent inducer of apoptosis, which activates both cell-survival and cell-death mechanisms simultaneously.
Abstract: Out of the almost 17 members of the TNF superfamily, TNF is probably the most potent inducer of apoptosis. TNF activates both cell-survival and cell-death mechanisms simultaneously. Activation of NF-kB-dependent genes regulates the survival and proliferative effects pf TNF, whereas activation of caspases regulates the apoptotic effects. TNF-induced apoptosis is mediated primarily through the activation of type I receptors, the death domain of which recruits more than a dozen different signaling proteins, which together are considered part of an apoptotic cascade. This cascade does not, however, account for the role of reactive oxygen intermediates, ceramide, phospholipases, and serine proteases which are also inplicated in TNF-induced apoptosis. This cascade also does not explain how type II TNF receptors which lack the death domain, induce apoptosis. Nevertheless, this review of apoptosis signaling will be limited to those proteins that makeup the cascade.
456 citations
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TL;DR: This study suggests targeted interventions to create a positive space for study among students from the vulnerable section of society and strategies are urgently needed to build a resilient education system in the state.
455 citations
Authors
Showing all 6255 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ashok Kumar | 151 | 5654 | 164086 |
Rajesh Kumar | 149 | 4439 | 140830 |
Sanjay Gupta | 99 | 902 | 35039 |
Rakesh Kumar | 91 | 1959 | 39017 |
Praveen Kumar | 88 | 1339 | 35718 |
Rajendra Prasad | 86 | 945 | 29526 |
Mukesh K. Jain | 85 | 539 | 27485 |
Shiv Kumar Sarin | 84 | 740 | 28368 |
Gaurav Sharma | 82 | 1244 | 31482 |
Santosh Kumar | 80 | 1196 | 29391 |
Dinesh Mohan | 79 | 283 | 35775 |
Govindjee | 76 | 426 | 21800 |
Dipak K. Das | 75 | 327 | 17708 |
Amit Verma | 70 | 497 | 16162 |
Manoj Kumar | 65 | 408 | 16838 |