Long Island University

About: Long Island University is a education organization based out in Brookville, New York, United States. It is known for research contribution in the topics: Population & Context (language use). The organization has 2647 authors who have published 4924 publications receiving 108757 citations.

Authoritative Classroom Management: How Control and Nurturance Work Together

Abstract: Despite broad recognition that teaching excellence requires meeting students' intellectual and social needs, teachers struggle to manage—and learning theory struggles to explain—the interplay between the academic and social dimensions of classroom life. Drawing from research on parenting and child development, the author offers parenting style theory as an explanatory framework. The author begins by describing the two primary dimensions of parenting style (control and nurturance) and the influence of various styles on children's learning and development. The author then discusses the two primary channels whereby style functions, using case studies of three classrooms to illustrate how control and nurturance interact to influence student engagement and learning. Finally, the author argues that because this theory is intuitive, robust, and comprehensive, it is an important vehicle for advancing understanding of teacher influence on student outcomes and school improvement efforts.

2,3-Bifunctionalized Quinoxalines: Synthesis, DNA Interactions and Evaluation of Anticancer, Anti-tuberculosis and Antifungal Activity

Abstract: A variety of 2,3-bifunctionalized quinoxalines (6-14) have been prepared by the condensation of 1,6-disubstituted-hexan-1,3,4,6-tetraones (1-4) with o-phenylenediamine, (R,R)-1,2-diaminocyclohexane and p-nitro-o-phenylenediamine. It is concluded that strong intramolecular N-H----O bonds in the favoured keto-enamine form may be responsible for the minimal biological activities observed in DNA footprinting, antitubercular, anti-fungal and anticancer tests with these hyper π-conjugated quinoxaline derivatives. However, subtle alteration by addition of a nitro group affecting the charge distribution confers significant improvements in biological effects and binding to DNA.

RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition

Abstract: Retinoic acid receptors (RARs) are ligand-dependent transcription factors which are members of the steroid/thyroid hormone receptor gene family. RAR-agonists inhibit the proliferation of many human breast cancer cell lines, particularly those whose growth is stimulated by estradiol (E2) or growth factors. PCR-amplified subtractive hybridization was used to identify candidate retinoid-regulated genes that may be involved in growth inhibition. One candidate gene identified was SOX9, a member of the high mobility group (HMG) box gene family of transcription factors. SOX9 gene expression is rapidly stimulated by RAR-agonists in T-47D cells and other retinoid-inhibited breast cancer cell lines. In support of this finding, a database search indicates that SOX9 is expressed as an EST in breast tumor cells. SOX9 is known to be expressed in chondrocytes where it regulates the transcription of type II collagen and in testes where it plays a role in male sexual differentiation. RAR pan-agonists and the RARalpha-selective agonist Am580, but not RXR agonists, stimulate the expression of SOX9 in a wide variety of retinoid-inhibited breast cancer cell lines. RAR-agonists did not stimulate SOX9 in breast cancer cell lines which were not growth inhibited by retinoids. Expression of SOX9 in T-47D cells leads to cycle changes similar to those found with RAR-agonists while expression of a dominant negative form of SOX9 blocks RA-mediated cell cycle changes, suggesting a role for SOX9 in retinoid-mediated growth inhibition.

Impact of Commercialization of the Internet on International Trade: A Panel Study Using the Extended Gravity Model

Abstract: This article tests the proposition that information and communication technology (ICT) and the Internet have enhanced international trade. Until recently, a sufficiently lengthy series of data as not available to make valid comparisons of international trade before and after the commercialization of the Internet. The use of balanced panel data for 64 countries (representing many phases of economic development) for the years 1985 to 2005 and the instrumental variable approach of Hausman and Taylor and other panel data methods provide an adequate basis for our conclusions. The results of the study are unequivocal and robust. There is a positive and significant effect of ICT infrastructure and the availability of the Internet for commercial transactions on the volume of international trade.

Impact of methamphetamine on infection and immunity

Abstract: The prevalence of methamphetamine (METH) use is estimated at ~35 million people worldwide, with over 10 million users in the United States. METH use elicits a myriad of social consequences and the behavioral impact of the drug is well understood. However, new information has recently emerged detailing the devastating effects of METH on host immunity, increasing the acquisition of diverse pathogens and exacerbating the severity of disease. These outcomes manifest as modifications in protective physical and chemical defenses, pro-inflammatory responses, and the induction of oxidative stress pathways. Through these processes, significant neurotoxicities arise, and, as such, chronic abusers with these conditions are at a higher risk for heightened consequences. METH use also influences the adaptive immune response, permitting the unrestrained development of opportunistic diseases. In this review, we discuss recent literature addressing the impact of METH on infection and immunity, and identify areas ripe for future investigation.