Pusan National University

About: Pusan National University is a education organization based out in Busan, South Korea. It is known for research contribution in the topics: Catalysis & Population. The organization has 24124 authors who have published 45054 publications receiving 819356 citations. The organization is also known as: Busan National University & Pusan University.

Insulin-like Growth Factor II Induced by Hypoxia May Contribute to Angiogenesis of Human Hepatocellular Carcinoma

Abstract: Insulin-like growth factor II (IGF-II) is highly expressed during hepatocarcinogenesis (P. Schirmacher et al. , Cancer Res., 52: 2549–2556, 1992; B. C. Park et al. , J. Hepatol., 22: 286–294, 1995). However, the mechanism of its enhanced expression is largely unknown. In this study, we show that IGF-II mRNA levels are increased within six h of exposing human hepatoma cell cultures to hypoxia, suggesting that hypoxia may be a strong stimulus for the induction of IGF-II expression in the process of hepatocarcinogenesis. This finding and the fact that hepatocellular carcinoma (HCC) is a typical hypervascular tumor (M. Mise et al. , Hepatology, 23: 455–464, 1996) imply that IGF-II may play an important role in the development of neovascularization of HCC. Here we demonstrate that IGF-II substantially increases vascular endothelial growth factor (VEGF) mRNA and protein levels in a time-dependent manner in human hepatoma cells. The induction of VEGF by IGF-II was additively increased by hypoxia. Moreover, the direct angiogenic activity of IGF-II was observed in the quantitative chick chorioallantoic membrane assay (M. Nguyen et al. , Microvasc. Res., 47: 31–40, 1994). These data suggest that IGF-II may be a hypoxia-inducible angiogenic factor in HCC.

K∗(892)0 and φ(1020) production in Pb-Pb collisions at sNN =2.76 TeV

Abstract: The yields of the K*(892)(0) and phi(1020) resonances are measured in Pb-Pb collisions at root s(NN) = 2.76 TeV through their hadronic decays using the ALICE detector. The measurements are performed in multiple centrality intervals at mid-rapidity (vertical bar y vertical bar <0.5) in the transverse-momentum ranges 0.3

3D porous layered double hydroxides grown on graphene as advanced electrochemical pseudocapacitor materials

Abstract: A 3D hybrid nickel-aluminum layered double hydroxide (NiAl-LDH)–graphene nanosheets (GNS) composite as a supercapacitor material has been fabricated by in situ deposition of LDH nanosheets on graphene oxide (GO) through a liquid phase deposition method. The results reveal that NiAl-LDH homogeneously grew on the surface of GNS as spacers to keep the neighboring sheets separate. Optimum effects could be achieved when feeding ratio, reaction time and temperature are tuned. The obtained porous GNS/NiAl-LDH composite exhibited high-capacitance performance with a specific capacitance of 1255.8 F g−1 at a current density of 1 A g−1 and 755.6 F g−1 at 6 A g−1, respectively. Moreover, the composite exhibited excellent cycling performance with an increase of 6% capacitance compared with the initial capacitance after 1500 cycle tests. Such high specific capacitance, rate capability and exceptional cycling ability of the composite offered great promise in energy storage device applications.