Pusan National University

About: Pusan National University is a education organization based out in Busan, South Korea. It is known for research contribution in the topics: Catalysis & Population. The organization has 24124 authors who have published 45054 publications receiving 819356 citations. The organization is also known as: Busan National University & Pusan University.

Two‐photon stereolithography for realizing ultraprecise three‐dimensional nano/microdevices

Abstract: Two-photon stereolithography (TPS) provides many advantages for achieving two-dimensional (2D) and three-dimensional (3D) micrometer-scale polymeric, ceramic and metallic structures applicable to complicated optical and neo-electronic microdevices. In the fabrication of high-resolution 3D microstructures, TPS has significant advantages over conventional microelectromechanical system (MEMS) processing, which involves time-consuming multistep indirect fabrication processes. Many studies have recently been made to develop and improve the TPS process, focusing on creating greater efficiency, higher resolution, and greater productivity, which are essential requirements of a practical TPS process. For the first time, an artistic microstructure has recently been successfully produced with an ultraprecise spatial resolution, sub-30 nm nanofibers, 3D multilayer imprint stamps for mass production, and ceramic 3D microstructures. In this review, we report the progress of two-photon polymerization based on 3D microfabrication, including the results obtained from the original research. This report is presented in three sections: improvement of resolution, precise design schemes, and applications of 3D microstructures.

Prognostic value of volumetric parameters of (18)F-FDG PET in non-small-cell lung cancer: a meta-analysis.

Abstract: Purpose We conducted a comprehensive systematic review of the literature on volumetric parameters from 18F-FDG PET and a meta-analysis of the prognostic value of metabolic tumour volume (MTV) and total lesion glycolysis (TLG) in patients with lung cancer.

Angiogenesis and Its Therapeutic Opportunities

Abstract: Angiogenesis plays critical roles in human physiology that range from reproduction and fetal growth to wound healing and tissue repair. The sophisticated multistep process is tightly regulated in a spatial and temporal manner by “on-off switch signals” between angiogenic factors, extracellular matrix components, and endothelial cells. Uncontrolled angiogenesis may lead to several angiogenic disorders, including vascular insufficiency (myocardial or critical limb ischemia) and vascular overgrowth (hemangiomas, vascularized tumors, and retinopathies). Thus, numerous therapeutic opportunities can be envisaged through the successful understanding and subsequent manipulation of angiogenesis. Here, we review the clinical implications of angiogenesis and discuss pro- and antiangiogenic agents that offer potential therapy for cancer and other angiogenic diseases.

Smoking and rheumatoid arthritis.

Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory disease caused by both genetic and environmental factors. Smoking has been implicated as one of the most important extrinsic risk factors for its development and severity. Recent developments have shed light on the pathophysiology of RA in smokers, including oxidative stress, inflammation, autoantibody formation and epigenetic changes. The association of smoking and the development of RA have been demonstrated through epidemiologic studies, as well as through in vivo and animal models of RA. With increased use of biological agents in addition to standard disease-modifying antirheumatic drugs (DMARDs), there has been interest in how smoking affects drug response in RA treatment. Recent evidence suggests the response and drug survival in people treated with anti-tumour necrosis factor (anti-TNF) therapy is poorer in heavy smokers, and possible immunological mechanisms for this effect are presented in the current paper.

Observation of D0 meson nuclear modifications in Au+Au collisions at sNN =200GeV

Abstract: We report the first measurement of charmed-hadron (D-0) production via the hadronic decay channel (D-0 -> K- + pi(+)) in Au + Au collisions at root(NN)-N-s = 200 GeV with the STAR experiment. The charm production cross section per nucleon- nucleon collision at midrapidity scales with the number of binary collisions, N-bin, from p + p to central Au + Au collisions. The D-0 meson yields in central Au + Au collisions are strongly suppressed compared to those in p + p scaled by N-bin, for transverse momenta p(T) > 3 GeV/c, demonstrating significant energy loss of charm quarks in the hot and dense medium. An enhancement at intermediate p(T) is also observed. Model calculations including strong charm-medium interactions and coalescence hadronization describe our measurements.