Institution
Torrey Pines Institute for Molecular Studies
Nonprofit•San Diego, California, United States•
About: Torrey Pines Institute for Molecular Studies is a nonprofit organization based out in San Diego, California, United States. It is known for research contribution in the topics: Antigen & T cell. The organization has 2323 authors who have published 2217 publications receiving 112618 citations.
Topics: Antigen, T cell, Peptide, Solid-phase synthesis, Cytotoxic T cell
Papers published on a yearly basis
Papers
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TL;DR: To fully access the breadth of structural, biological and functional information associated with structural genomics data, multiple document clients (such as structure visualizers and web-browsers) are often required to be open simultaneously.
41 citations
41 citations
TL;DR: The results show that p53 is required for the bleomycin-induced cerebellar granule cell death, and raise the possibility that c-Jun is necessary for p53-dependent neuronal apoptosis induced by bleomyin.
41 citations
TL;DR: Challenges remain in the application of gene therapy techniques to skin substitutes, both the control of transgene expression and in the selection of suitable genes to transfect, and a challenge that may be diminishing is the importance of acute rejection of allogeneic tissue-engineered skin substitutes.
Abstract: The development of tissue engineered skin substitutes has reached a mature stage; major remaining questions relate to areas of greatest potential utility. Research is mainly concerned with extending indications of existing products, including treatment of the full range of acute, chronic, surgical and cosmetic wounds, and in other applications such as soft tissue augmentation and gene delivery. Among the few advances in the composition of skin substitutes is the inclusion of endothelial cells to provide a pathway for vascularisation by the host system.
40 citations
TL;DR: Bead-bound or, preferably, positional scanning synthetic and soluble combinatorial peptide libraries allow the identification of T-cell epitopes within complex mixtures of proteins even for T cells that have been expanded from an organ infiltrate with a polyclonal stimulus.
40 citations
Authors
Showing all 2327 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Eric J. Topol | 193 | 1373 | 151025 |
| John R. Yates | 177 | 1036 | 129029 |
| George F. Koob | 171 | 935 | 112521 |
| Ian A. Wilson | 158 | 971 | 98221 |
| Peter G. Schultz | 156 | 893 | 89716 |
| Gerald M. Edelman | 147 | 545 | 69091 |
| Floyd E. Bloom | 139 | 616 | 72641 |
| Stuart A. Lipton | 134 | 488 | 71297 |
| Benjamin F. Cravatt | 131 | 666 | 61932 |
| Chi-Huey Wong | 129 | 1220 | 66349 |
| Klaus Ley | 129 | 495 | 57964 |
| Nicholas J. Schork | 125 | 587 | 62131 |
| Michael Andreeff | 117 | 959 | 54734 |
| Susan L. McElroy | 117 | 570 | 44992 |
| Peter E. Wright | 115 | 444 | 55388 |