Universidade de Pernambuco

About: Universidade de Pernambuco is a education organization based out in Recife, Brazil. It is known for research contribution in the topics: Population & Medicine. The organization has 6147 authors who have published 6948 publications receiving 73648 citations.

Global hippocampal atrophy in major depressive disorder: a meta-analysis of magnetic resonance imaging studies.

Abstract: Introduction: Major depressive disorder (MDD), an incapacitating mental disorder, is characterized by episodes of at least 2 weeks of apparent changes in mood, cognition, and neurovegetative functions. Many neuroimaging studies using magnetic resonance imaging (MRI) have examined morphometric changes in patients with MDD, but the results are not conclusive. This study aims to review the literature and perform a meta-analysis on hippocampal volume (HcV) in patients with MDD. Methods: Studies on HcV in patients with MDD diagnosis were identified from major databases (MEDLINE, EMBASE, The Cochrane Library, Scopus, PsycINFO, and SciELO) using the search terms depression, major depressive disorder, MDD, unipolar, magnetic resonance imaging, MRI, and hippocampus. Results: A meta-analysis of 29 studies fulfilling specific criteria was performed. The sample included 1327 patients and 1004 healthy participants. The studies were highly heterogeneous with respect to age, sex, age of onset, and average illness duration. However, the pooled effect size of depression was significant in both hippocampi. MDD was associated with right (-0.43; 95% confidence interval [95%CI] −0.66 to −0.21) and left (-0.40; 95%CI −0.66 to −0.15) hippocampal atrophy. Conclusions: MDD seems to be associated with global HcV atrophy. Larger longitudinal follow-up studies designed to analyze the influence of sociodemographic variables on this relationship are required to yield better evidence about this topic.

Heart rate variability and its relationship with central and general obesity in obese normotensive adolescents

Abstract: OBJECTIVE: To analyze the relationship between the heart rate variability parameters and the indicators of central and general obesity in obese normotensive adolescents. METHODS: Seventyfour 13 to 18 year-old obese normotensive adolescents participated in this study. The indicators analyzed for central and general obesity were waist circumference and body mass index, respectively. Heart rate variability was obtained by heart rate monitoring. For this, the adolescents remained in a supine position for 7 minutes with controlled breathing. Parameters were obtained in time domain (standard deviation of all the RR intervals, root mean square of successive differences between the normal adjacent RR intervals and the percentage of adjacent intervals with more than 50ms) and frequency domain variables (low and high frequency bands and the sympathovagal balance). RESULTS: After adjustments for gender, age, and cardiorespiratory fitness, a negative correlation between the waist circumference and the root mean square of successive differences between the normal adjacent RR intervals (s=-1.51; standard error=0.56; p 0.05). CONCLUSION: Central obesity is a better discriminator than general obesity of autonomic cardiac dysfunction in obese normotensive adolescents.

Violence against women, family cohesion and drugs

Abstract: OBJETIVO: Avaliar a associacao entre coesao, adaptabilidade e risco mental familiar com violencia fisica contra a mulher e uso de drogas. METODOS: Estudo tipo caso-controle pareado realizado entre 2004 e 2005 na cidade de Joao Pessoa, Paraiba. A amostra foi constituida por 260 mulheres, divididas em 130 agredidas e 130 nao agredidas. O grupo caso foi constituido de mulheres que prestaram queixa por agressao fisica domestica na Delegacia Especializada da Mulher. O grupo controle foi pareado com mulheres vizinhas de bairro das vitimas queixosas na Delegacia. A coesao, a adaptabilidade e o risco mental foram avaliados pela escala Family Adaptability and Cohesion Evaluation Scales. Na analise estatistica, foram utilizados os testes qui-quadrado e Exato de Fisher, com nivel de significância de 5%. RESULTADOS: Os dois grupos se comportaram de forma diferente em relacao ao risco mental e coesao, mas semelhantes quanto a adaptabilidade familiar (p=0,0917). As mulheres agredidas apresentaram risco mental alto (43,1%) e medio (39,2%), diferentemente das nao agredidas (p=0,0016), que apresentaram medio risco (55,4%). Houve diferenca significativa entre os dois grupos para o uso de drogas, com consumo maior nas familias das mulheres agredidas (90,8%) do que das nao agredidas (56,9%). A droga mais utilizada foi o alcool, sendo o mais alto fator de risco para a agressao, quando consumido diariamente (OR=37,33) ou associado a outra droga (OR=29,56). CONCLUSOES: O desequilibrio pela falta de uniao entre a familia e o uso de drogas altera decisivamente no funcionamento familiar, podendo gerar conflitos e agressoes domesticas.

CloudML: An Integrated Language for Resource, Service and Request Description for D-Clouds

Abstract: Distributed Clouds, or just D-Clouds, can be seen as a paradigm that is able to exploit the potential of sharing resources across geographic boundaries and provide latency-bound allocation of resources to third-party developers. The representation of D-Cloud resources is a challenge that involves the careful choice of characteristics that drive the mapping of requests on the substrate resources. Regarding these problems, this paper introduces the Cloud Modeling Language (CloudML), a vendor-neutral XML-based language intended to integrate the description of different cloud related aspects such as computational and network resources, services profiles, and developers' requests in an integrated way. Furthermore, the CloudML provides a way to describe geographical location aware services, seen particularly indispensable in D-Cloud scenarios.

Tumores odontogênicos: estudo clínico-patológico de 238 casos

Abstract: Os tumores odontogenicos sao neoplasias que se desenvolvem exclusivamente nos ossos gnaticos, originando-se dos tecidos odontogenicos por proliferacao de tecido epitelial, mesenquimal ou ambos. OBJETIVO: Avaliar a incidencia de tumores odontogenicos em determinada instituicao e comparar com outros estudos da literatura mundial. FORMA DE ESTUDO: Estudo de coorte transversal. MATERIAL E METODO: O material do estudo foi levantado a partir dos registros de pacientes com tumores odontogenicos, no periodo de janeiro de 1992 a marco de 2007 (15 anos). Foram incluidos os casos de pacientes que se enquadravam na Classificacao Histologica da Organizacao Mundial de Saude (OMS) de 2005. Foram analisados os indicadores genero, faixa etaria, localizacao anatomica, tipo histologico e presenca de sintomatologia. RESULTADOS: Os tumores odontogenicos constituiram 4,76% dentre todas as lesoes biopsiadas dentro do periodo estudado. A idade media dos pacientes foi de 30,7 anos, 57% dos pacientes eram do genero masculino. O tumor odontogenico ceratocistico foi o tipo histologico mais prevalente (30%), seguido do ameloblastoma (23,7%). Quanto a presenca de sintomatologia, 75,7% dos casos apresentaram-se assintomaticos. CONCLUSAO: Os tumores odontogenicos parecem ter discreta predilecao pelo genero feminino, segunda e terceira decadas de vida, sendo mais frequentes na mandibula e, na maioria dos casos apresentam-se assintomaticos.