Institution
Universidade de Pernambuco
Education•Recife, Brazil•
About: Universidade de Pernambuco is a education organization based out in Recife, Brazil. It is known for research contribution in the topics: Population & Medicine. The organization has 6147 authors who have published 6948 publications receiving 73648 citations.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: It is proved that methoxy or chloro substitution on phenyl ring at para-position is fundamental for in vitro activity of new spiroacridine derivatives, and indicates that AMTAC-06 is a promising entity and should serve as a lead compound in the development of new DNA and protein binders, as well as human topoisomerase II inhibitors.
28 citations
••
TL;DR: The effectiveness of high‐frequency transcutaneous electrical nerve stimulation (TENS) as a pain relief resource for primiparous puerpere who had experienced natural childbirth with an episiotomy was evaluated.
Abstract: Aim: We evaluated the effectiveness of high-frequency transcutaneous electrical nerve stimulation (TENS) as a pain relief resource for primiparous puerpere who had experienced natural childbirth with an episiotomy.
Methods: A controlled, randomized clinical study was conducted in a Brazilian maternity ward. Forty puerpere were randomly divided into two groups: TENS high frequency and a no treatment control group. Post-episiotomy pain was assessed in the resting and sitting positions and during ambulation. An 11-point numeric rating scale was performed in three separate evaluations (at the beginning of the study, after 60 min and after 120 min). The McGill pain questionnaire was employed at the beginning and 60 min later. TENS with 100 Hz frequency and 75 µs pulse for 60 min was employed without causing any pain. Four electrodes ware placed in parallel near the episiotomy site, in the area of the pudendal and genitofemoral nerves.
Results: An 11-point numeric rating scale and McGill pain questionnaire showed a significant statistical difference in pain reduction in the TENS group, while the control group showed no alteration in the level of discomfort. Hence, high-frequency TENS treatment significantly reduced pain intensity immediately after its use and 60 min later.
Conclusion: TENS is a safe and viable non-pharmacological analgesic resource to be employed for pain relief post-episiotomy. The routine use of TENS post-episiotomy is recommended.
28 citations
••
TL;DR: Curcumin has a toxic effect on microorganisms at appreciable concentrations upon photoactivation, however, it was required to use the maximum concentration of the drug for a successful procedure.
Abstract: Objective: This investigation assessed the susceptibility of Streptococcus mutans and Lactobacillus acidophilus to Photodynamic Therapy (PDT) when grown simultaneously in dentine carious lesions. Background data: PDT is a technique that utilizes light to activate photosensitizers in the presence of oxygen to produce reactive radicals. Materials and methods: A culture medium of 1% glucose, 2% sucrose, 1% young primary culture of L. acidophilus 108 CFU/mL, and S. mutans 108 CFU/mL was utilized to inoculate the bacterial induced caries on human dentine slabs. Different concentrations of the photosensitizer (0.75, 1.5, 3.0, 4.0, and 5.0 g/L) were activated through exposure to the light-emitting diode source with a central wavelength of 450 nm and a fluency of 5.7 J/cm2. Two light intensities (19 and 47.5 mW/cm2) were tested. Four different groups were analyzed: L−D− (control group), L−D+ (drug group), L+D+1 (PDT group 1, light intensity of 19 mW/cm2), and L+D+2 (PDT group 2, light intensity of 47.5 m...
28 citations
••
TL;DR: The negative self-perception of smile was statistically associated with severity of occlusal disorders according to the DAI scores, which suggests that self- perception should be used together with standard clinical criteria when decisions about orthodontic treatments are made in public health care systems.
Abstract: This study estimated the prevalence of negative self-perception of smile because of occlusion abnormalities and investigated their association according to standard clinical criteria. The sample consisted of 1290 randomly selected Brazilian adolescent boys and girls aged 12-16 years. The outcome of interest was dissatisfaction with smile, and data were collected using a standardized questionnaire. Occlusion characteristics were assessed using the dental aesthetic index (DAI). The other study variables were gender, age, and use of dental services. A chi-square test and Poisson multiple regression were used for statistical analysis. Of the 1290 students interviewed and examined, 539 (41.8 per cent) were dissatisfied with their smile; of these, 373 (69.2 per cent) assigned their dissatisfaction to the presence of an occlusal abnormality, and 166 (30.8 per cent) reported reasons other than occlusal abnormalities for their negative self-perception of their smile. In multivariate analysis, the following variables were associated with the outcome of interest: maxillary anterior irregularity [prevalence ratio (PR) = 1.40; 95 per cent confidence interval (CI) = 1.29-1.80], incisal spacing (PR = 1.37; 95 per cent CI = 1.19-1.57), vertical open bite (PR = 1.34; 95 per cent CI = 1.15-1.55), mandibular anterior irregularity (PR = 1.29; 95 per cent CI = 1.14-1.46), permanent anterior teeth missing (PR = 1.21; 95 per cent CI = 1.05-1.39), and incisal diastema (PR = 1.14; 95 per cent CI = 1.01-1.31). The negative self-perception of smile was statistically associated with severity of occlusal disorders according to the DAI scores, which suggests that self-perception should be used together with standard clinical criteria when decisions about orthodontic treatments are made in public health care systems.
28 citations
••
TL;DR: The genetic etiology of the Liberfarb syndrome, affecting brain, eye, ear, bone, bone and connective tissue, is identified and the migration of a rare Portuguese founder variant to two continents is highlighted.
28 citations
Authors
Showing all 6197 results
Name | H-index | Papers | Citations |
---|---|---|---|
Laura C. Rodrigues | 75 | 431 | 21539 |
José Guilherme Cecatti | 56 | 414 | 10550 |
Anibal Faundes | 51 | 314 | 10714 |
Robert E. Condon | 48 | 192 | 7376 |
Ricardo Almeida | 43 | 250 | 7304 |
Mark A. Carlson | 41 | 206 | 7844 |
Ricardo Arraes de Alencar Ximenes | 36 | 181 | 4414 |
Ivan G. Costa | 36 | 129 | 3740 |
Tshilidzi Marwala | 35 | 525 | 5596 |
Cláudia Lúcia de Moraes Forjaz | 34 | 202 | 4549 |
Nelson Wolosker | 33 | 348 | 4416 |
Raphael Mendes Ritti-Dias | 32 | 277 | 11334 |
Marcelo Moraes Valença | 32 | 207 | 3702 |
Mauro Virgílio Gomes de Barros | 32 | 163 | 8608 |
Rômulo Araújo Fernandes | 31 | 290 | 6403 |