Institution
University of Münster
Education•Münster, Germany•
About: University of Münster is a education organization based out in Münster, Germany. It is known for research contribution in the topics: Population & Catalysis. The organization has 35609 authors who have published 69059 publications receiving 2278534 citations. The organization is also known as: University of Munster & University of Muenster.
Topics: Population, Catalysis, Transplantation, Gene, Crystal structure
Papers published on a yearly basis
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01 Apr 2012-Materials Science and Engineering A-structural Materials Properties Microstructure and Processing
TL;DR: Grain boundaries in ultrafine grained (UFG) materials processed by severe plastic deformation (SPD) are often called “non-equilibrium” grain boundaries.
Abstract: Grain boundaries in ultrafine grained (UFG) materials processed by severe plastic deformation (SPD) are often called “non-equilibrium” grain boundaries. Such boundaries are characterized by excess grain boundary energy, presence of long range elastic stresses and enhanced free volumes. These features and related phenomena (diffusion, segregation, etc.) have been the object of intense studies and the obtained results provide convincing evidence of the importance of a non-equilibrium state of high angle grain boundaries for UFG materials with unusual properties. The aims of the present paper are first to give a short overview of this research field and then to consider tangled, yet unclear issues and outline the ways of oncoming studies. A special emphasis is given on the specific structure of grain boundaries in ultrafine grained materials processed by SPD, on grain boundary segregation, on interfacial mixing linked to heterophase boundaries and on grain boundary diffusion. The connection between these unique features and the mechanical properties or the thermal stability of the ultrafine grained alloys is also discussed.
427 citations
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TL;DR: It is indicated that functional PSGL-1 is expressed on platelets, and this work suggests an additional mechanism by which selectins and their ligands participate in inflammatory and/or hemostatic responses.
Abstract: The platelet plays a pivotal role in maintaining vascular integrity. In a manner similar to leukocytes, platelets interact with selectins expressed on activated endothelium. P-selectin glycoprotein ligand 1 (PSGL-1) is the main P-selectin ligand expressed on leukocytes. Searching for platelet ligand(s), we used a P-selectin–immunoglobulin G (IgG) chimera to affinity purify surface-biotinylated proteins from platelet lysates. P-selectin–bound ligands were eluted with ethylenediaminetetraacetic acid. An ∼210-kD biotinylated protein was isolated from both human neutrophil and platelet preparations. A band of the same size was also immunopurified from human platelets using a monoclonal anti–human PSGL-1 antibody and could be blotted with P-selectin–IgG. Under reducing conditions, both the predicted PSGL-1 ∼210-kD dimer and the ∼120-kD monomer were isolated from platelets. Comparative immunoelectron microscopy and Western blotting experiments suggested that platelet PSGL-1 expression is 25–100-fold lower than that of leukocytes. However, patients with chronic idiopathic thrombocytopenic purpura who harbor predominantly young platelets displayed greater expression, indicating that PSGL-1 expression may be decreased during platelet aging. By flow cytometry, thrombin-activated platelets from normal individuals exhibited greater expression than those unstimulated. An inhibitory anti–PSGL-1 antibody significantly reduced platelet rolling in mesenteric venules, as observed by intravital microscopy. Our results indicate that functional PSGL-1 is expressed on platelets, and suggest an additional mechanism by which selectins and their ligands participate in inflammatory and/or hemostatic responses.
427 citations
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TL;DR: In patients with atrial fibrillation who had PCI, the edoxaban- based regimen was non-inferior for bleeding compared with the VKA-based regimen, without significant differences in ischaemic events.
427 citations
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TL;DR: In this paper, the authors derived a static potential for a heavy quark- antiquark pair propagating in Minkowski time at finite temperature, by defining a suitable gauge-invariant Green's function and computing it to first non-trivial order in Hard Thermal Loop resummed perturbation theory.
Abstract: We derive a static potential for a heavy quark- antiquark pair propagating in Minkowski time at finite temperature, by defining a suitable gauge-invariant Green's function and computing it to first non-trivial order in Hard Thermal Loop resummed perturbation theory. The resulting Debye- screened potential could be used in models that attempt to describe the "melting" of heavy quarkonium at high temperatures. We show, in particular, that the potential develops an imaginary part, implying that thermal e effects ects generate a finite width for the quarkonium peak in the dilepton production rate. For quarkonium with a very heavy constituent mass M, the width can be ignored for T <= g(2)M/12 pi, where g2 is the strong gauge coupling; for a physical case like bottomonium, it could become important at temperatures as low as 250 MeV. Finally, we point out that the physics related to the finite width originates from the Landau-damping of low-frequency gauge fields, and could be studied non-perturbatively by making use of the classical approximation.
427 citations
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University of Southern California1, University of Surrey2, Royal Surrey County Hospital3, University of California, San Diego4, Emory University5, University of California, San Francisco6, University of Münster7, University of Dundee8, University of Florida9, Ghent University Hospital10, Baystate Medical Center11, Cincinnati Children's Hospital Medical Center12, Brigham and Women's Hospital13, Innsbruck Medical University14, Mayo Clinic15, University of Chicago16, King Chulalongkorn Memorial Hospital17, Columbia University18, University of Alberta19, Wuhan University20, Queen Mary University of London21, Royal Society22, University of Alabama at Birmingham23, Washington University in St. Louis24, Health Science University25, Peking University26, University of Padua27, University of Pittsburgh28
TL;DR: This Consensus Statement from the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI and for areas of future research, with the aim of improving understanding of the underlying processes and outcomes for patients with CO VID- 19 AKI.
Abstract: Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) requiring renal replacement therapy (RRT; also known as kidney replacement therapy). COVID-19-associated AKI (COVID-19 AKI) is associated with high mortality and serves as an independent risk factor for all-cause in-hospital death in patients with COVID-19. The pathophysiology and mechanisms of AKI in patients with COVID-19 have not been fully elucidated and seem to be multifactorial, in keeping with the pathophysiology of AKI in other patients who are critically ill. Little is known about the prevention and management of COVID-19 AKI. The emergence of regional 'surges' in COVID-19 cases can limit hospital resources, including dialysis availability and supplies; thus, careful daily assessment of available resources is needed. In this Consensus Statement, the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI based on current literature. We also make recommendations for areas of future research, which are aimed at improving understanding of the underlying processes and improving outcomes for patients with COVID-19 AKI.
427 citations
Authors
Showing all 36075 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hyun-Chul Kim | 176 | 4076 | 183227 |
Klaus Müllen | 164 | 2125 | 140748 |
Giacomo Bruno | 158 | 1687 | 124368 |
Anders M. Dale | 156 | 823 | 133891 |
Holger J. Schünemann | 141 | 810 | 113169 |
Joachim Heinrich | 136 | 1309 | 76887 |
Markus Merschmeyer | 132 | 1188 | 84975 |
Klaus Ley | 129 | 495 | 57964 |
Robert W. Mahley | 128 | 363 | 60774 |
Robert J. Kurman | 127 | 397 | 60277 |
Bart Barlogie | 126 | 779 | 57803 |
Thomas Schwarz | 123 | 701 | 54560 |
Carlos Caldas | 122 | 547 | 73840 |
Klaus Weber | 121 | 524 | 60346 |
Andrey L. Rogach | 117 | 576 | 46820 |