University of Warwick

About: University of Warwick is a education organization based out in Coventry, Warwickshire, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 26212 authors who have published 77127 publications receiving 2666552 citations. The organization is also known as: Warwick University & The University of Warwick.

Innovation in Governance and Public Services: Past and Present

Abstract: Three approaches to innovation in the public sector in the post war period are identified and analysed for their implications for policy-makers, managers and citizens. Various relationships are identified between innovation and improvement in public services. The traditional bias of the literature that innovation is necessarily functional is undermined. Important lessons for policy, practice and research include the need to develop an understanding of innovation which is not over-reliant on the private sector manufacturing literature but reflects the distinctive contexts and purposes of the public sector.

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

Abstract: We present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the US Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference RNA samples with built-in controls, we assess RNA sequencing (RNA-seq) performance for junction discovery and differential expression profiling and compare it to microarray and quantitative PCR (qPCR) data using complementary metrics. At all sequencing depths, we discover unannotated exon-exon junctions, with >80% validated by qPCR. We find that measurements of relative expression are accurate and reproducible across sites and platforms if specific filters are used. In contrast, RNA-seq and microarrays do not provide accurate absolute measurements, and gene-specific biases are observed for all examined platforms, including qPCR. Measurement performance depends on the platform and data analysis pipeline, and variation is large for transcript-level profiling. The complete SEQC data sets, comprising >100 billion reads (10Tb), provide unique resources for evaluating RNA-seq analyses for clinical and regulatory settings.

Observation of $J/\psi p$ Resonances Consistent with Pentaquark States in $\Lambda_b^0 \to J/\psi K^- p$ Decays

Abstract: Observations of exotic structures in the J/ψp channel, that we refer to as pentaquark-charmonium states, in Λ0b→J/ψK−p decays are presented. The data sample corresponds to an integrated luminosity of 3/fb acquired with the LHCb detector from 7 and 8 TeV pp collisions. An amplitude analysis is performed on the three-body final-state that reproduces the two-body mass and angular distributions. To obtain a satisfactory fit of the structures seen in the J/ψp mass spectrum, it is necessary to include two Breit-Wigner amplitudes that each describe a resonant state. The significance of each of these resonances is more than 9 standard deviations. One has a mass of 4380±8±29 MeV and a width of 205±18±86 MeV, while the second is narrower, with a mass of 4449.8±1.7±2.5 MeV and a width of 39±5±19 MeV. The preferred JP assignments are of opposite parity, with one state having spin 3/2 and the other 5/2.

Do Humans Have Two Systems to Track Beliefs and Belief-Like States?.

Abstract: The lack of consensus on how to characterize humans' capacity for belief reasoning has been brought into sharp focus by recent research. Children fail critical tests of belief reasoning before 3 to 4 years of age (H. Wellman, D. Cross, & J. Watson, 2001; H. Wimmer & J. Perner, 1983), yet infants apparently pass false-belief tasks at 13 or 15 months (K. H. Onishi & R. Baillargeon, 2005; L. Surian, S. Caldi, & D. Sperber, 2007). Nonhuman animals also fail critical tests of belief reasoning but can show very complex social behavior (e.g., J. Call & A Tomasello, 2005). Fluent social interaction in adult humans implies efficient processing of beliefs, yet direct tests suggest that belief reasoning is cognitively demanding, even for adults (e.g., I. A. Apperly, D. Samson, & G. W. Humphreys, 2009). The authors interpret these findings by drawing an analogy with the domain of number cognition, where similarly contrasting results have been observed. They propose that the success of infants and nonhuman animals on some belief reasoning tasks may be best explained by a cognitively efficient but inflexible capacity for tracking belief-like states. In humans, this capacity persists in parallel with a later-developing, more flexible but more cognitively demanding theory-of-mind abilities.

Concentrated solar power plants: Review and design methodology

Abstract: Concentrated solar power plants (CSPs) are gaining increasing interest, mostly as parabolic trough collectors (PTC) or solar tower collectors (STC). Notwithstanding CSP benefits, the daily and monthly variation of the solar irradiation flux is a main drawback. Despite the approximate match between hours of the day where solar radiation and energy demand peak, CSPs experience short term variations on cloudy days and cannot provide energy during night hours unless incorporating thermal energy storage (TES) and/or backup systems (BS) to operate continuously. To determine the optimum design and operation of the CSP throughout the year, whilst defining the required TES and/or BS, an accurate estimation of the daily solar irradiation is needed. Local solar irradiation data are mostly only available as monthly averages, and a predictive conversion into hourly data and direct irradiation is needed to provide a more accurate input into the CSP design. The paper (i) briefly reviews CSP technologies and STC advantages; (ii) presents a methodology to predict hourly beam (direct) irradiation from available monthly averages, based upon combined previous literature findings and available meteorological data; (iii) illustrates predictions for different selected STC locations; and finally (iv) describes the use of the predictions in simulating the required plant configuration of an optimum STC. The methodology and results demonstrate the potential of CSPs in general, whilst also defining the design background of STC plants.