University of Warwick

About: University of Warwick is a education organization based out in Coventry, Warwickshire, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 26212 authors who have published 77127 publications receiving 2666552 citations. The organization is also known as: Warwick University & The University of Warwick.

Trade Induced Technical Change? The Impact of Chinese Imports on Innovation, IT and Productivity

Abstract: We examine the impact of Chinese import competition on patenting, IT, RD and second it reallocated employment between firms towards more innovative and technologically advanced firms These within and between effects were about equal in magnitude, and appear to account for around 15% of European technology upgrading between 2000-2007 Rising Chinese import competition also led to falls in employment, profits, prices and the skill share By contrast, import competition from developed countries had no effect on innovation We develop a simple “trapped factor” model of innovation that is consistent with these empirical findings

Magnetic susceptibility of soil: an evaluation of conflicting theories using a national data set

Abstract: Magnetic susceptibility values for topsoils across England arc combined with data for soil type, geochemistry and concentrations of magnetotactic bacteria in order to evaluate different theories for explaining soil magnetism. Strongly magnetic soils in unpolluted areas are found over weakly magnetic substrates and are dominated by ultrafine superparamagnetic grains. Magnetotactic bacteria are present in insufficient concentrations to account for strongly magnetic soils, and crop burning is discounted as a major factor. A small number of samples show high values associated with either airborne magnetic particulates from pollution or residual primary ferrimagnetic minerals from igneous substrates. The results are used to construct a new mechanism for the formation of secondary ferrimagnetic minerals that links abiological weathering and biological fermentation processes. The fundamental driving force in the mechanism is Fe supply, which may be linked to climate. Observed causative associations between climate and the magnetic susceptibility of loess-palaeosol sequences are supported by the findings.

Nitrite as regulator of hypoxic signaling in mammalian physiology

Abstract: In this review we consider the effects of endogenous and pharmacological levels of nitrite under conditions of hypoxia. In humans, the nitrite anion has long been considered as metastable intermediate in the oxidation of nitric oxide radicals to the stable metabolite nitrate. This oxidation cascade was thought to be irreversible under physiological conditions. However, a growing body of experimental observations attests that the presence of endogenous nitrite regulates a number of signaling events along the physiological and pathophysiological oxygen gradient. Hypoxic signaling events include vasodilation, modulation of mitochondrial respiration, and cytoprotection following ischemic insult. These phenomena are attributed to the reduction of nitrite anions to nitric oxide if local oxygen levels in tissues decrease. Recent research identified a growing list of enzymatic and nonenzymatic pathways for this endogenous reduction of nitrite. Additional direct signaling events not involving free nitric oxide are proposed. We here discuss the mechanisms and properties of these various pathways and the role played by the local concentration of free oxygen in the affected tissue.

SME innovation, exporting and growth: A review of existing evidence

Abstract: SMEs which have a track record of innovation are more likely to export, more likely to export successfully, and more likely to generate growth from exporting than non-innovating firms. What are the factors that enable such performance? This paper summarises and synthesises the evidence on SME innovation, exporting and growth, paying particular attention to internal and external (eco-system) enablers, and for the interplay between innovation and exporting in SME growth. We highlight those areas for which the evidence base is secure and where the evidence base remains limited, and develop policy suggestions and an agenda for further research.

A high-density consensus map of barley linking DArT markers to SSR, RFLP and STS loci and agricultural traits

Abstract: Molecular marker technologies are undergoing a transition from largely serial assays measuring DNA fragment sizes to hybridization-based technologies with high multiplexing levels. Diversity Arrays Technology (DArT) is a hybridization-based technology that is increasingly being adopted by barley researchers. There is a need to integrate the information generated by DArT with previous data produced with gel-based marker technologies. The goal of this study was to build a high-density consensus linkage map from the combined datasets of ten populations, most of which were simultaneously typed with DArT and Simple Sequence Repeat (SSR), Restriction Enzyme Fragment Polymorphism (RFLP) and/or Sequence Tagged Site (STS) markers. The consensus map, built using a combination of JoinMap 3.0 software and several purpose-built perl scripts, comprised 2,935 loci (2,085 DArT, 850 other loci) and spanned 1,161 cM. It contained a total of 1,629 'bins' (unique loci), with an average inter-bin distance of 0.7 ± 1.0 cM (median = 0.3 cM). More than 98% of the map could be covered with a single DArT assay. The arrangement of loci was very similar to, and almost as optimal as, the arrangement of loci in component maps built for individual populations. The locus order of a synthetic map derived from merging the component maps without considering the segregation data was only slightly inferior. The distribution of loci along chromosomes indicated centromeric suppression of recombination in all chromosomes except 5H. DArT markers appeared to have a moderate tendency toward hypomethylated, gene-rich regions in distal chromosome areas. On the average, 14 ± 9 DArT loci were identified within 5 cM on either side of SSR, RFLP or STS loci previously identified as linked to agricultural traits. Our barley consensus map provides a framework for transferring genetic information between different marker systems and for deploying DArT markers in molecular breeding schemes. The study also highlights the need for improved software for building consensus maps from high-density segregation data of multiple populations.