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Journal ArticleDOI

Deep brain stimulation in the treatment of obsessive-compulsive disorder

TLDR
DBS is a promising treatment for therapy-refractory OCD, but the published experience is limited and the method is at present an experimental therapy.
About
This article is published in World Neurosurgery.The article was published on 2013-12-01. It has received 113 citations till now. The article focuses on the topics: Yale–Brown Obsessive Compulsive Scale & Deep brain stimulation.

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Citations
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Journal ArticleDOI

Deep brain stimulation.

TL;DR: Deep brain stimulation is clinically effective in improving motor function of essential tremor, Parkinson's disease and primary dystonia and in relieving obsessive-compulsive disorder.
Journal ArticleDOI

Resting-state networks link invasive and noninvasive brain stimulation across diverse psychiatric and neurological diseases.

TL;DR: It is found that although different types of brain stimulation are applied in different locations, targets used to treat the same disease most often are nodes within the same brain network as defined by resting-state functional-connectivity MRI.
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Selective Dysfunction of Basal Ganglia Subterritories: From Movement to Behavioral Disorders

TL;DR: Anatomical, experimental, and clinical data are reported to support the involvement of basal ganglia (BG) in cognitive and motivational functions in addition to motor control in Parkinson's disease and Gilles de la Tourette syndrome, which combine both motor and behavioral features.
References
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Journal ArticleDOI

Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease.

TL;DR: VIM stimulation strongly decreased the tremor but failed to suppress it as completely as thalamotomy did, due in part to the fact that programmable stimulator frequency rate is limited to 130 Hz, while it appeared that the optimal stimulation frequency was 200 Hz.
Journal ArticleDOI

Hold your horses: impulsivity, deep brain stimulation, and medication in parkinsonism.

TL;DR: It is shown that DBS selectively interferes with the normal ability to slow down when faced with decision conflict, which implicate independent mechanisms leading to impulsivity in treated Parkinson's patients and were predicted by a single neurocomputational model of the basal ganglia.
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Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression.

TL;DR: This study suggests that DBS is relatively safe and provides significant improvement in patients with TRD and likely acts by modulating brain networks whose dysfunction leads to depression.
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