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Deuterium magnetic resonance: theory and application to lipid membranes.

Joachim Seelig
- 01 Aug 1977 - 
- Vol. 10, Iss: 3, pp 353-418
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TLDR
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton-proton and proton–carbon dipolar interactions and are rather difficult to analyse.
Abstract
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton–proton and proton–carbon dipolar interactions. As a result the spectra contain a large number of overlapping resonances and are rather difficult to analyse. Nevertheless, important information on the structure and dynamic behaviour of lipid systems has been provided by these techniques (Wennerstrom & Lindblom, 1977).

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Cooperative organization of inorganic-surfactant and biomimetic assemblies

TL;DR: A model that makes use of the cooperative organization of inorganic and organic molecular species into three dimensionally structured arrays is generalized for the synthesis of nanocomposite materials to separate the effects of self-assembly from the kinetics of silicate polymerization.
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Lipid conformation in model membranes and biological membranes.

TL;DR: Protein molecules in solution or in protein crystals are characterized by rather well-defined structures in which α-helical regions, β-pleated sheets, etc., are the key features, and the double helix of nucleic acids has almost become the trademark of molecular biology as such.
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Mattress model of lipid-protein interactions in membranes

TL;DR: The model is used to interpret the influence of the lipid-protein interaction on calorimetric measurements and on local orientational order as determined by deuterium nuclear magnetic resonance.
Journal ArticleDOI

Interfacial catalysis: the mechanism of phospholipase A2

TL;DR: Comparison of the cobra-venom complex with the uninhibited PLA2 indicates that optimal binding and catalysis at the lipid-water interface is due to facilitated substrate diffusion from the interfacial binding surface to the catalytic site rather than an allosteric change in the enzyme's structure.
Journal ArticleDOI

Area per Lipid and Acyl Length Distributions in Fluid Phosphatidylcholines Determined by 2H NMR Spectroscopy

TL;DR: Experimental (2)H NMR measurements for the homologous series of 1, 2-diacyl-sn-glycero-3-phosphocholines with perdeuterated saturated chains show that the lateral packing of phospholipids is more sensitive to the headgroup methylation than to the acyl chain length.
References
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Book

Principles of magnetic resonance

TL;DR: In this article, the effect of changing the precession frequency of the magnetic field has been studied using NMR to study rate properties. But the effect is limited to the case of double and double resonance.
Book

Spin Labeling: Theory And Applications

TL;DR: This special topics volume represents a complete update on new theoretical aspects and applications of the spin-label method and includes an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations.
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