Deuterium magnetic resonance: theory and application to lipid membranes.
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TLDR
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton-proton and proton–carbon dipolar interactions and are rather difficult to analyse.Abstract:
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton–proton and proton–carbon dipolar interactions. As a result the spectra contain a large number of overlapping resonances and are rather difficult to analyse. Nevertheless, important information on the structure and dynamic behaviour of lipid systems has been provided by these techniques (Wennerstrom & Lindblom, 1977).read more
Citations
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Multiquantum filters and order in tissues.
TL;DR: This review deals mainly with the effect of anisotropic motion of water molecules and sodium ions in intact biological tissues on 2H, 1H and 23Na NMR spectroscopy and its application to NMR imaging (MRI).
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Alignment of lysine-anchored membrane peptides under conditions of hydrophobic mismatch: a CD, 15N and 31P solid-state NMR spectroscopy investigation.
Ulrike Harzer,Burkhard Bechinger +1 more
TL;DR: The secondary structure and alignment of hydrophobic model peptides in phosphatidylcholine membranes were investigated as a function ofhydrophobic mismatch by CD and oriented proton-decoupled NMR spectroscopies and a thermodynamic formalism was applied to describe the two-state equilibrium between in-plane and transmembrane peptide orientations.
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Partitioning of local anesthetics into membranes: surface charge effects monitored by the phospholipid head-group
TL;DR: Deuterium magnetic resonance demonstrated that the binding of drug changed the head-group conformation of the lipid molecules, and a linear variation of the deuterium quadrupole splittings of the choline segments with the surface charge density was observed, suggesting that the phosphocholine head- group may act as a 'molecular electrometer' with respect to surface charges.
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Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipid-cholesterol bilayers.
TL;DR: The results demonstrate the ability of cholesterol to adjust the structural and dynamic properties of membranes composed of different phospholipid components, and to efficiently regulate the motional freedom and hydrophobicity of membranes, so that they can withstand even drastic changes in environmental conditions, such as high external hydrostatic pressure.
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Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. I. Scaling of neutron data and the distributions of double bonds and water
TL;DR: The scaling of the neutron data and the determination of the transbilayer distribution of double bonds in liquid-crystalline (L alpha phase) phospholipid bilayers of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) indicate that the maximum separation along the bilayer normal between the double bonds of the acyl chains is 1 A or less.
References
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Book
Principles of magnetic resonance
TL;DR: In this article, the effect of changing the precession frequency of the magnetic field has been studied using NMR to study rate properties. But the effect is limited to the case of double and double resonance.
Journal ArticleDOI
Molecular motion in spin-labeled phospholipids and membranes
Book
Spin Labeling: Theory And Applications
TL;DR: This special topics volume represents a complete update on new theoretical aspects and applications of the spin-label method and includes an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations.