Deuterium magnetic resonance: theory and application to lipid membranes.
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TLDR
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton-proton and proton–carbon dipolar interactions and are rather difficult to analyse.Abstract:
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton–proton and proton–carbon dipolar interactions. As a result the spectra contain a large number of overlapping resonances and are rather difficult to analyse. Nevertheless, important information on the structure and dynamic behaviour of lipid systems has been provided by these techniques (Wennerstrom & Lindblom, 1977).read more
Citations
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Low pH acts as inhibitor of membrane damage induced by human islet amyloid polypeptide.
Lucie Khemtémourian,Lucie Khemtémourian,Elena Doménech,Jacques P.F. Doux,Martijn C. Koorengevel,J. Antoinette Killian +5 more
TL;DR: This study suggests that a low pH prevents aggregation and membrane damage of IAPP in the secretory granules, most likely by affecting the ionization properties of the peptide.
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Solid-state NMR and rigid body molecular dynamics to determine domain orientations of monomeric phospholamban.
TL;DR: Solid-state NMR spectroscopy shows that monomeric phospholamban in lipid bilayers has two distinct helical domains, with an interhelical angle within 60-100 degrees, ruling out the possibility of a continuous alpha-helical structure for this protein.
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The headgroup conformation of phospholipids in membranes.
Georg Büldt,Roland Wohlgemuth +1 more
TL;DR: Considering lipid influence on membrane protein function, the work of Overath, Schairer and Stoffel (1970) gives an example of the way in which the lipid state influences sugar transport through membranes of Escherichia coli which were enriched in some lipid species.
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Conformational Order of DMPC sn-1 versus sn-2 Chains and Membrane Thickness: An Approach to Molecular Protrusion by Solid State 2H-NMR and Neutron Diffraction
TL;DR: In this article, the ordering properties of sn-1 and sn-2 dimyristoylphosphatidylcholine (DMPC) chains were investigated by NMR and neutron diffraction in order to relate membrane defects to bilayer thickness.
References
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Book
Principles of magnetic resonance
TL;DR: In this article, the effect of changing the precession frequency of the magnetic field has been studied using NMR to study rate properties. But the effect is limited to the case of double and double resonance.
Journal ArticleDOI
Molecular motion in spin-labeled phospholipids and membranes
Book
Spin Labeling: Theory And Applications
TL;DR: This special topics volume represents a complete update on new theoretical aspects and applications of the spin-label method and includes an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations.