Deuterium magnetic resonance: theory and application to lipid membranes.
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TLDR
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton-proton and proton–carbon dipolar interactions and are rather difficult to analyse.Abstract:
Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton–proton and proton–carbon dipolar interactions. As a result the spectra contain a large number of overlapping resonances and are rather difficult to analyse. Nevertheless, important information on the structure and dynamic behaviour of lipid systems has been provided by these techniques (Wennerstrom & Lindblom, 1977).read more
Citations
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2H NMR and polyelectrolyte–surfactant interactions: from micelles to monolayers to membranes
TL;DR: In this paper, deuterium (2H) NMR studies of polyelectrolytes interacting with deutero-labeled surfactants in different surfactant self-assembled architectures, including micelles, monolayers, and bilayer membranes, are presented.
Journal ArticleDOI
Multiple quantum spectrum of oriented hexane-d6
TL;DR: In this paper, the proton multiple quantum NMR (MQ NMR) spectrum of methyl-deuterated hexane-d 6 was obtained in a nematic solvent.
Journal ArticleDOI
Alteration of Membrane Physicochemical Properties by Two Factors for Membrane Protein Integration
Kaoru Nomura,Toshiyuki Yamaguchi,Shoko Mori,Kohki Fujikawa,Ken-ichi Nishiyama,Toshinori Shimanouchi,Yasushi Tanimoto,Kenichi Morigaki,Keiko Shimamoto +8 more
TL;DR: By manipulating the membrane lipids dynamics, DAG inhibits the protein from contacting the inner membrane, whereas the flexible long sugar chain of MPIase increases the opportunity for interaction between the membrane and the protein, leading to membrane integration of the newly formed protein.
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2H-NMR studies on ether lipid-rich bacterial membranes: deuterium order profile of Clostridium butyricum
TL;DR: The ordering of the deuterated hydrocarbon chains in whole cells was measured with deuterium nuclear magnetic resonance and was compared to the order profiles of isolated cell membranes and membranes formed from the total phospholipid extract, which have the same characteristic shape as those found for the lamellar liquid-crystalline phases of synthetic diacylphospholipids.
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The dynamics and orientation of a lipophilic drug within model membranes determined by 13C solid-state NMR
Martin Boland,David A. Middleton +1 more
TL;DR: A novel combination of high-resolution solid-state nuclear magnetic resonance (SSNMR) methods and selective broadening of (13)C NMR peaks by paramagnetic Mn(2+) together suggest a model for the location, orientation and dynamics of the drug within lipid bilayers that offers an explanation for the lysoprotective effect of thedrug at low concentrations.
References
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Book
Principles of magnetic resonance
TL;DR: In this article, the effect of changing the precession frequency of the magnetic field has been studied using NMR to study rate properties. But the effect is limited to the case of double and double resonance.
Journal ArticleDOI
Molecular motion in spin-labeled phospholipids and membranes
Book
Spin Labeling: Theory And Applications
TL;DR: This special topics volume represents a complete update on new theoretical aspects and applications of the spin-label method and includes an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations.