Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning.
TLDR
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people hospitalized with severe COVID-19 illness has engendered considerable interest in the metabolic aspects of SARS-CoV-2-induced pathophysiology as mentioned in this paper.About:
This article is published in Cell Metabolism.The article was published on 2021-03-02 and is currently open access. It has received 145 citations till now. The article focuses on the topics: Diabetes mellitus.read more
Citations
More filters
Journal ArticleDOI
Female gender is associated with long COVID syndrome: a prospective cohort study
TL;DR: In this article , the authors explored the association between female gender and long COVID syndrome, defined as persistence of physical and/or psychological symptoms for more than 4 weeks after recovery from acute COVID-19 disease.
Journal ArticleDOI
Female gender is associated with “long COVID” syndrome: a prospective cohort study
Francesca Bai,Daniele Tomasoni,Camilla Falcinella,Diletta Barbanotti,Roberto Castoldi,Giovanni Mulè,Matteo Augello,Debora Mondatore,Marina Allegrini,Andrea Cona,Daniele Tesoro,Gianmarco Tagliaferri,Ottavia Viganò,Elisa Suardi,Camilla Tincati,Tomaso Beringheli,Benedetta Varisco,Chiara Luridiana Battistini,Kyrie Piscopo,Elena Vegni,Alessandro Tavelli,Stefano Terzoni,Giulia Marchetti,Antonella d'Arminio Monforte +23 more
TL;DR: In this article, the authors explored the association between female gender and long COVID syndrome, defined as persistence of physical and/or psychological symptoms for more than 4 weeks after recovery from acute COVID-19 disease.
Journal ArticleDOI
Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine.
Raul Pellini,Aldo Venuti,Fulvia Pimpinelli,Elva Abril,Giovanni Blandino,Flaminia Campo,Laura Conti,Armando De Virgilio,Federico De Marco,Enea Gino Di Domenico,Ornella Di Bella,Simona di Martino,Fabrizio Ensoli,Diana Giannarelli,Chiara Mandoj,Valentina Manciocco,Paolo Marchesi,Francesco Mazzola,Silvia Moretto,Gerardo Petruzzi,Fabrizio Petrone,Barbara Pichi,Martina Pontone,Jacopo Zocchi,Antonello Vidiri,Branka Vujovic,Giulia Piaggio,Aldo Morrone,Gennaro Ciliberto +28 more
TL;DR: In this paper, the antibody titre changes in correlation with age, gender, BMI and hypertension were analyzed in a group of 248 healthcare workers after the second dose of BNT162b2 vaccine.
Journal ArticleDOI
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Moritz Reiterer,Mangala Rajan,Nicolás Gómez-Banoy,Jennifer D. Lau,Luis Gomez-Escobar,Lunkun Ma,Ankit Gilani,Sergio Alvarez-Mulett,Evan Sholle,Vasuretha Chandar,Yaron Bram,Katherine Hoffman,Priya Bhardwaj,Phoebe Piloco,Alfonso Rubio-Navarro,Skyler Uhl,Lucia Carrau,Sean Houhgton,David Redmond,Alpana P. Shukla,Parag Goyal,Kristy A. Brown,Benjamin R. tenOever,Laura C. Alonso,Robert E. Schwartz,Edward J. Schenck,Monika M. Safford,James C. Lo +27 more
TL;DR: In this article, a screen of glucoregulatory hormones revealed lower levels of adiponectin in patients with acute respiratory distress syndrome (ARDS) and COVID-19 status.
Journal ArticleDOI
Immune cell-mediated features of non-alcoholic steatohepatitis.
Thierry Huby,Emmanuel L. Gautier +1 more
TL;DR: In this paper, the authors discuss current concepts related to the role of immune cells in the onset and progression of NASH, and a better understanding of the mechanisms by which immune cells contribute to NASH pathogenesis should aid the design of innovative drugs to target NASH.
References
More filters
Journal ArticleDOI
Diabetes Epidemiology in the COVID-19 Pandemic.
TL;DR: It is argued that the COVID-19 pandemic is a defining moment for the field of epidemiology and that diabetes epidemiology should play a significant role and opportunities for future epidemiologic studies are discussed.
Journal ArticleDOI
Obesity as a risk factor for COVID-19 mortality in women and men in the UK Biobank: comparisons with influenza/pneumonia and coronary heart disease
TL;DR: It is shown that the relative effects of a higher BMI on COVID‐19 mortality may be stronger in women than men and that the association between higher BMI and the risk of influenza/pneumonia death in men is similar between the sexes.
Journal ArticleDOI
The Neutrophil-to-Lymphocyte Ratio Determines Clinical Efficacy of Corticosteroid Therapy in Patients with COVID-19.
Jingjing Cai,Jingjing Cai,Haomiao Li,Changjiang Zhang,Ze Chen,Hui Liu,Fang Lei,Juan Juan Qin,Ye Mao Liu,Feng Zhou,Xiaohui Song,Jianghua Zhou,Yan Ci Zhao,Bin Wu,Meiling He,Huilin Yang,Lihua Zhu,Peng Zhang,Yan Xiao Ji,Guang Nian Zhao,Zhigang Lu,Liming Liu,Weiming Mao,Xiaofeng Liao,Haofeng Lu,Daihong Wang,Xigang Xia,Xiaodong Huang,Xiang Wei,Jiahong Xia,Bing Hong Zhang,Yufeng Yuan,Zhi-Gang She,Qingbo Xu,Xin-Liang Ma,Yibin Wang,Juan Yang,Xin Zhang,Xiao Jing Zhang,Hongliang Li +39 more
TL;DR: Wang et al. as discussed by the authors found that neutrophil-to-lymphocyte ratio (NLR) > 6.11 at admission discriminated a higher risk for mortality, however, corticosteroid treatment in such individuals was associated with a lower risk of 60-day all-cause mortality.
Journal ArticleDOI
Clinical, laboratory, and temporal predictors of neutralizing antibodies against SARS-CoV-2 among COVID-19 convalescent plasma donor candidates.
Jim Boonyaratanakornkit,Chihiro Morishima,Stacy Selke,Danniel Zamora,Danniel Zamora,Sarah A. McGuffin,Adrienne E Shapiro,Victoria L. Campbell,Christopher L. McClurkan,Lichen Jing,Robin Gross,Janie Liang,Elena Postnikova,Steven Mazur,Vladimir V. Lukin,Anu Chaudhary,Marie K. Das,Susan L. Fink,Andrew Bryan,Alexander L. Greninger,Keith R. Jerome,Michael R. Holbrook,Terry Gernsheimer,Terry Gernsheimer,Mark H. Wener,Anna Wald,Anna Wald,David M. Koelle +27 more
TL;DR: Functional nAb levels were found to decline and a small proportion of persons recovered from COVID-19 lack adaptive immune responses, although standard commercially available SARS-CoV-2 IgG results can serve as useful surrogates for nAb testing.
Journal ArticleDOI
EFFECT oF STATIN THERAPY oN SARS-CoV-2 INFECTION-RELATED.
Lluís Masana,Eudald Correig,Cèlia Rodríguez-Borjabad,Eva Anoro,Juan Antonio Arroyo,Carlos Jericó,Àngels Pedragosa,Marcel la Miret,Silvia Näf,Anna Pardo,Verónica Perea,Rosa Pérez-Bernalte,Núria Plana,Rafael Ramírez-Montesinos,Meritxell Royuela,Cristina Soler,Maria Urquizu-Padilla,Alberto Zamora,J. Pedro-Botet +18 more
TL;DR: A lower SARS-CoV-2 infection-related mortality was observed in patients treated with statin therapy prior to hospitalization and Statin therapy should not be discontinued due to the global concern of the pandemic or in patients hospitalized for COVID-19.
Related Papers (5)
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes.
Lihua Zhu,Zhi-Gang She,Xu Cheng,Juan Juan Qin,Xiao Jing Zhang,Jingjing Cai,Fang Lei,Haitao Wang,Jing Xie,Wenxin Wang,Haomiao Li,Peng Zhang,Xiaohui Song,Xi Chen,Xiang Mei,Chaozheng Zhang,Liangjie Bai,Da Xiang,Ming Ming Chen,Yanqiong Liu,Youqin Yan,Mingyu Liu,Weiming Mao,Jinjing Zou,Liming Liu,Guohua Chen,Pengcheng Luo,Bing Xiao,Changjiang Zhang,Zixiong Zhang,Zhigang Lu,Junhai Wang,Haofeng Lu,Xigang Xia,Daihong Wang,Xiaofeng Liao,Gang Peng,Ping Ye,Jun Yang,Yufeng Yuan,Xiaodong Huang,Jiao Guo,Bing Hong Zhang,Hongliang Li +43 more
COVID-19 and diabetes mellitus: from pathophysiology to clinical management.
Factors associated with COVID-19-related death using OpenSAFELY.
Elizabeth A. Williamson,Alex J Walker,Krishnan Bhaskaran,Seb Bacon,Chris Bates,Caroline E Morton,Helen J Curtis,Amir Mehrkar,David M. Evans,Peter Inglesby,Jonathan Cockburn,Helen Mcdonald,Brian MacKenna,Laurie A. Tomlinson,Ian J. Douglas,Christopher T Rentsch,Rohini Mathur,Angel Y S Wong,Richard Grieve,David G. Harrison,Harriet Forbes,Anna Schultze,Richard Croker,John Parry,Frank Hester,Sam Harper,Rafael Perera,Stephen J. W. Evans,Liam Smeeth,Ben Goldacre +29 more