Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning.
TLDR
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people hospitalized with severe COVID-19 illness has engendered considerable interest in the metabolic aspects of SARS-CoV-2-induced pathophysiology as mentioned in this paper.About:
This article is published in Cell Metabolism.The article was published on 2021-03-02 and is currently open access. It has received 145 citations till now. The article focuses on the topics: Diabetes mellitus.read more
Citations
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Female gender is associated with long COVID syndrome: a prospective cohort study
TL;DR: In this article , the authors explored the association between female gender and long COVID syndrome, defined as persistence of physical and/or psychological symptoms for more than 4 weeks after recovery from acute COVID-19 disease.
Journal ArticleDOI
Female gender is associated with “long COVID” syndrome: a prospective cohort study
Francesca Bai,Daniele Tomasoni,Camilla Falcinella,Diletta Barbanotti,Roberto Castoldi,Giovanni Mulè,Matteo Augello,Debora Mondatore,Marina Allegrini,Andrea Cona,Daniele Tesoro,Gianmarco Tagliaferri,Ottavia Viganò,Elisa Suardi,Camilla Tincati,Tomaso Beringheli,Benedetta Varisco,Chiara Luridiana Battistini,Kyrie Piscopo,Elena Vegni,Alessandro Tavelli,Stefano Terzoni,Giulia Marchetti,Antonella d'Arminio Monforte +23 more
TL;DR: In this article, the authors explored the association between female gender and long COVID syndrome, defined as persistence of physical and/or psychological symptoms for more than 4 weeks after recovery from acute COVID-19 disease.
Journal ArticleDOI
Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine.
Raul Pellini,Aldo Venuti,Fulvia Pimpinelli,Elva Abril,Giovanni Blandino,Flaminia Campo,Laura Conti,Armando De Virgilio,Federico De Marco,Enea Gino Di Domenico,Ornella Di Bella,Simona di Martino,Fabrizio Ensoli,Diana Giannarelli,Chiara Mandoj,Valentina Manciocco,Paolo Marchesi,Francesco Mazzola,Silvia Moretto,Gerardo Petruzzi,Fabrizio Petrone,Barbara Pichi,Martina Pontone,Jacopo Zocchi,Antonello Vidiri,Branka Vujovic,Giulia Piaggio,Aldo Morrone,Gennaro Ciliberto +28 more
TL;DR: In this paper, the antibody titre changes in correlation with age, gender, BMI and hypertension were analyzed in a group of 248 healthcare workers after the second dose of BNT162b2 vaccine.
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Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Moritz Reiterer,Mangala Rajan,Nicolás Gómez-Banoy,Jennifer D. Lau,Luis Gomez-Escobar,Lunkun Ma,Ankit Gilani,Sergio Alvarez-Mulett,Evan Sholle,Vasuretha Chandar,Yaron Bram,Katherine Hoffman,Priya Bhardwaj,Phoebe Piloco,Alfonso Rubio-Navarro,Skyler Uhl,Lucia Carrau,Sean Houhgton,David Redmond,Alpana P. Shukla,Parag Goyal,Kristy A. Brown,Benjamin R. tenOever,Laura C. Alonso,Robert E. Schwartz,Edward J. Schenck,Monika M. Safford,James C. Lo +27 more
TL;DR: In this article, a screen of glucoregulatory hormones revealed lower levels of adiponectin in patients with acute respiratory distress syndrome (ARDS) and COVID-19 status.
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Immune cell-mediated features of non-alcoholic steatohepatitis.
Thierry Huby,Emmanuel L. Gautier +1 more
TL;DR: In this paper, the authors discuss current concepts related to the role of immune cells in the onset and progression of NASH, and a better understanding of the mechanisms by which immune cells contribute to NASH pathogenesis should aid the design of innovative drugs to target NASH.
References
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Type 2 Diabetes and COVID-19-Related Mortality in the Critical Care Setting: A National Cohort Study in England, March-July 2020.
John M Dennis,Bilal A. Mateen,Raphael Sonabend,Nicholas J. Thomas,Nicholas J. Thomas,Kashyap A. Patel,Kashyap A. Patel,Andrew T. Hattersley,Andrew T. Hattersley,Spiros Denaxas,Spiros Denaxas,Andrew P. McGovern,Andrew P. McGovern,Sebastian J. Vollmer,Sebastian J. Vollmer +14 more
TL;DR: Type 2 diabetes may be an independent prognostic factor for survival in people with severe COVID-19 requiring critical care treatment, and in this setting the risk increase associated with type 2 diabetes is greatest in younger people.
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Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth.
Danielle M. Fernandes,Carlos R. Oliveira,Sandra Guerguis,Ruth Eisenberg,Jaeun Choi,Mimi Y. Kim,Ashraf Abdelhemid,Rabia Agha,Saranga Agarwal,Judy L. Aschner,Jeffrey R. Avner,Cathleen Ballance,Joshua Bock,Sejal M. Bhavsar,Melissa Campbell,Katharine N. Clouser,Matthew Gesner,David L. Goldman,Margaret R. Hammerschlag,Saul R. Hymes,Ashley Howard,Hee jin Jung,Stephan Kohlhoff,Tsoline Kojaoghlanian,Rachel Lewis,Sharon Nachman,Srividya Naganathan,Elijah Paintsil,Harpreet Pall,Sharlene Sy,Stephen Wadowski,Elissa Zirinsky,Michael D. Cabana,Betsy C. Herold +33 more
TL;DR: In this paper, the authors identify demographic and clinical features of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) syndromes and identify admission variables predictive of disease severity.
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Did the COVID-19 Lockdown Affect the Incidence of Pediatric Type 1 Diabetes in Germany?
Sascha R. Tittel,Joachim Rosenbauer,Clemens Kamrath,Julian Ziegler,Felix Reschke,Johanna Hammersen,Kirsten Mönkemöller,Angeliki Pappa,Thomas Kapellen,Reinhard W. Holl +9 more
TL;DR: Over the past few months, coronavirus disease 2019 (COVID-19) and subsequent social distancing have affected biological, psychological, economic, and social aspects of life.
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Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19.
Aakriti Gupta,Mahesh V. Madhavan,Timothy J. Poterucha,Ersilia M. DeFilippis,Jessica A. Hennessey,Björn Redfors,Björn Redfors,Christina Eckhardt,Behnood Bikdeli,Behnood Bikdeli,Jonathan Platt,Ani Nalbandian,Pierre Elias,Matthew J. Cummings,Shayan Nabavi Nouri,Matthew Lawlor,Lauren S. Ranard,Jianhua Li,Claudia Boyle,Raymond Givens,Daniel Brodie,Harlan M. Krumholz,Gregg W. Stone,Sanjum S. Sethi,Daniel Burkhoff,Nir Uriel,Allan Schwartz,Martin B. Leon,Ajay J. Kirtane,Elaine Wan,Sahil A. Parikh +30 more
TL;DR: In this article, a multivariable logistic regression model was constructed to predict the propensity of receiving statins, adjusting for baseline sociodemographic and clinical characteristics, and outpatient medications.
Journal ArticleDOI
Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes.
TL;DR: In this paper, a retrospective electronic health record data analysis of 25,326 subjects tested for COVID-19 between 2/25/20 and 6/22/20 at the University of Alabama at Birmingham Hospital, a tertiary health care center in the racially diverse Southern U.S.
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