Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning.
TLDR
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people hospitalized with severe COVID-19 illness has engendered considerable interest in the metabolic aspects of SARS-CoV-2-induced pathophysiology as mentioned in this paper.About:
This article is published in Cell Metabolism.The article was published on 2021-03-02 and is currently open access. It has received 145 citations till now. The article focuses on the topics: Diabetes mellitus.read more
Citations
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Female gender is associated with long COVID syndrome: a prospective cohort study
TL;DR: In this article , the authors explored the association between female gender and long COVID syndrome, defined as persistence of physical and/or psychological symptoms for more than 4 weeks after recovery from acute COVID-19 disease.
Journal ArticleDOI
Female gender is associated with “long COVID” syndrome: a prospective cohort study
Francesca Bai,Daniele Tomasoni,Camilla Falcinella,Diletta Barbanotti,Roberto Castoldi,Giovanni Mulè,Matteo Augello,Debora Mondatore,Marina Allegrini,Andrea Cona,Daniele Tesoro,Gianmarco Tagliaferri,Ottavia Viganò,Elisa Suardi,Camilla Tincati,Tomaso Beringheli,Benedetta Varisco,Chiara Luridiana Battistini,Kyrie Piscopo,Elena Vegni,Alessandro Tavelli,Stefano Terzoni,Giulia Marchetti,Antonella d'Arminio Monforte +23 more
TL;DR: In this article, the authors explored the association between female gender and long COVID syndrome, defined as persistence of physical and/or psychological symptoms for more than 4 weeks after recovery from acute COVID-19 disease.
Journal ArticleDOI
Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine.
Raul Pellini,Aldo Venuti,Fulvia Pimpinelli,Elva Abril,Giovanni Blandino,Flaminia Campo,Laura Conti,Armando De Virgilio,Federico De Marco,Enea Gino Di Domenico,Ornella Di Bella,Simona di Martino,Fabrizio Ensoli,Diana Giannarelli,Chiara Mandoj,Valentina Manciocco,Paolo Marchesi,Francesco Mazzola,Silvia Moretto,Gerardo Petruzzi,Fabrizio Petrone,Barbara Pichi,Martina Pontone,Jacopo Zocchi,Antonello Vidiri,Branka Vujovic,Giulia Piaggio,Aldo Morrone,Gennaro Ciliberto +28 more
TL;DR: In this paper, the antibody titre changes in correlation with age, gender, BMI and hypertension were analyzed in a group of 248 healthcare workers after the second dose of BNT162b2 vaccine.
Journal ArticleDOI
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Moritz Reiterer,Mangala Rajan,Nicolás Gómez-Banoy,Jennifer D. Lau,Luis Gomez-Escobar,Lunkun Ma,Ankit Gilani,Sergio Alvarez-Mulett,Evan Sholle,Vasuretha Chandar,Yaron Bram,Katherine Hoffman,Priya Bhardwaj,Phoebe Piloco,Alfonso Rubio-Navarro,Skyler Uhl,Lucia Carrau,Sean Houhgton,David Redmond,Alpana P. Shukla,Parag Goyal,Kristy A. Brown,Benjamin R. tenOever,Laura C. Alonso,Robert E. Schwartz,Edward J. Schenck,Monika M. Safford,James C. Lo +27 more
TL;DR: In this article, a screen of glucoregulatory hormones revealed lower levels of adiponectin in patients with acute respiratory distress syndrome (ARDS) and COVID-19 status.
Journal ArticleDOI
Immune cell-mediated features of non-alcoholic steatohepatitis.
Thierry Huby,Emmanuel L. Gautier +1 more
TL;DR: In this paper, the authors discuss current concepts related to the role of immune cells in the onset and progression of NASH, and a better understanding of the mechanisms by which immune cells contribute to NASH pathogenesis should aid the design of innovative drugs to target NASH.
References
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Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study.
Vito Lampasona,Massimiliano Secchi,Marina Scavini,Elena Bazzigaluppi,Cristina Brigatti,Ilaria Marzinotto,Alberto M. Davalli,Amelia Caretto,Andrea Laurenzi,S. Martinenghi,Chiara Molinari,Giordano Vitali,Luigi di Filippo,Alessia Mercalli,Raffaella Melzi,Cristina Tresoldi,Patrizia Rovere-Querini,Giovanni Landoni,Fabio Ciceri,Emanuele Bosi,Lorenzo Piemonti +20 more
TL;DR: The humoral response against SARS-CoV-2 in patients with diabetes was present and superimposable, as for timing and antibody titres, to that of non-diabetic patients, with marginal differences, and was not influenced by glucose levels.
Journal ArticleDOI
Obesity Doubles Mortality in Patients Hospitalized for Severe Acute Respiratory Syndrome Coronavirus 2 in Paris Hospitals, France: A Cohort Study on 5,795 Patients.
Sébastien Czernichow,Sébastien Czernichow,Nathanaël Beeker,Claire Rives-Lange,Claire Rives-Lange,Emmanuel Guerot,Jean-Luc Diehl,Sandrine Katsahian,Jean-Sébastien Hulot,Tigran Poghosyan,Claire Carette,Anne-Sophie Jannot +11 more
TL;DR: The strength of association between obesity in patients hospitalized with coronavirus disease 2019 (COVID‐19) and mortality and the risk according to usual cardiometabolic risk factors in a large cohort are described.
Journal ArticleDOI
Obesity prolongs the hospital stay in patients affected by COVID-19, and may impact on SARS-COV-2 shedding.
Diego Moriconi,Stefano Masi,Eleni Rebelos,Agostino Virdis,Maria Laura Manca,Salvatore De Marco,Stefano Taddei,Monica Nannipieri +7 more
TL;DR: Subjects with obesity affected by COVID-19 require longer hospitalization, more intensive and longer oxygen treatment, and they may have longer SARS-COV-2 shedding.
Journal ArticleDOI
Type 1 diabetes onset triggered by COVID-19.
TL;DR: There was a short delay between COVID-19 infection and diabetes onset, and it remains to determine if the hyperinflammation/ cytokine storm described with this infection could accelerate the onset of type 1 diabetes in genetically susceptible individuals.
Journal ArticleDOI
Statin Use and In-Hospital Mortality in Patients With Diabetes Mellitus and COVID-19.
Omar Saeed,Francesco Castagna,Ilir Agalliu,Xiaonan Xue,Snehal R. Patel,Yogita Rochlani,Rachna Kataria,Sasa Vukelic,Daniel B. Sims,Chikezie Alvarez,Mercedes Rivas-Lasarte,Mario J. Garcia,Ulrich P. Jorde +12 more
TL;DR: Statin use was associated with reduced in‐hospital mortality from COVID‐19 in patients with diabetes mellitus, and these findings, if validated, may further reemphasize administration of statins to patients with Diabetes mellitus during the CO VID‐19 era.
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