Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis.
Qianquan Ma,Qianquan Ma,Changsheng Xing,Wenyong Long,Helen Yicheng Wang,Qing Liu,Rongfu Wang,Rongfu Wang,Rongfu Wang +8 more
TLDR
The biological interplay between gut-brain axis is discussed, and how this communication may be dysregulated in neurological diseases is explored, and new insights in modification of gut microbiota composition are highlighted.Abstract:
Development of central nervous system (CNS) is regulated by both intrinsic and peripheral signals. Previous studies have suggested that environmental factors affect neurological activities under both physiological and pathological conditions. Although there is anatomical separation, emerging evidence has indicated the existence of bidirectional interaction between gut microbiota, i.e., (diverse microorganisms colonizing human intestine), and brain. The cross-talk between gut microbiota and brain may have crucial impact during basic neurogenerative processes, in neurodegenerative disorders and tumors of CNS. In this review, we discuss the biological interplay between gut-brain axis, and further explore how this communication may be dysregulated in neurological diseases. Further, we highlight new insights in modification of gut microbiota composition, which may emerge as a promising therapeutic approach to treat CNS disorders.read more
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Microbiota in anorexia nervosa: potential for treatment
TL;DR: A review of the role of the gut microbiota in the pathogenesis and treatment of anorexia nervosa is presented in this article , where the authors focus on the bidirectional interaction between the gastrointestinal tract and the central nervous system (microbiota-gut brain axis).
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Crosstalk between the aging intestinal microflora and the brain in ischemic stroke
TL;DR: Preclinical and clinical studies on the role of the aged microbiota-gut-brain axis in the development of risk factors for stroke and changes in the post-stroke microflora are presented.
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Exploring the potential of prebiotic and polyphenol-based dietary interventions for the alleviation of cognitive and gastrointestinal perturbations associated with military specific stressors
TL;DR: The link between prebiotics, polyphenols and cognitive and gastrointestinal health, and the effects that PTSD and related gastrointestinal issues have on health and wellbeing is investigated.
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A Common Research Hypothesis for Crohn Disease, Ulcerative Colitis, Psoriasis and Acquired Vitiligo
TL;DR: In pathogenesis of disease of autoimmune origin, the psycho immuno-axis, as known today, is incomplete or even non-existent and the mind of the sufferer is presumed to have an influence on hypersensitive tissue damage reaction, but the probable linkage with its weaponry at molecular level, the authors mean cytokines, is missing.
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