Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
Citations
More filters
Journal ArticleDOI
Synergistic Modulation of Carbon-Based, Precious-Metal-Free Electrocatalysts for Oxygen Reduction Reaction.
TL;DR: In this paper, a review of carbon-based, precious-metal-free nanocatalysts with synergistic modulation of active-site species and their exposure, mass transfer, and charge transport during the electrochemical process is presented.
Journal ArticleDOI
Atom Transfer Radical Polymerization in the Solid-State.
TL;DR: Investigation of the data revealed that the solid‐state polymerization reaction was controlled, followed a mechanism similar to that described for solution‐state atom transfer radical polymerizations, and may be used to prepare polymers that are inaccessible via solution‐ state methods.
Journal ArticleDOI
The Black Polymorph of TTF-CA: TTF Polymorphism and Solvent Effects in Mechanochemical and Vapor Digestion Syntheses, FT-IR, Crystal Packing, and Electronic Structure
Saul H. Lapidus,Amit Naik,Alex I. Wixtrom,Néstor E. Massa,Vinh Ta Phuoc,Leire del Campo,Sébastien Lebègue,Sébastien Lebègue,János G. Ángyán,János G. Ángyán,Tarek M. Abdel-Fattah,Silvina Pagola +11 more
TL;DR: In this paper, the effects of small quantities of LAG solvent and solvent vapors in VD toward the formation of a particular TTF-CA product polymorph were studied from both tetrathiafulvalene forms (orange and brown) as reactants.
Journal ArticleDOI
Ambient Temperature Graphitization Based on Mechanochemical Synthesis
Yating Yuan,Tao Wang,Hao Chen,Shannon M. Mahurin,Huimin Luo,Gabriel M. Veith,Zhenzhen Yang,Zhenzhen Yang,Sheng Dai,Sheng Dai +9 more
TL;DR: A mechanochemical approach is demonstrated to afford highly crystalline graphite nanosheets at ambient temperature using a carbon nitride framework driven by a denitriding reaction in the presence of magnesium, which is promoted by mechanochemistry.
Journal ArticleDOI
In situ monitoring of vapour-induced assembly of pharmaceutical cocrystals using a benchtop powder X-ray diffractometer
TL;DR: Proof-of-principle application of a simple setup for in situ continuous monitoring of vapour-induced transformations of organic solids using a benchtop powder X-ray diffractometer to model pharmaceutical cocrystals reveals complex reactivity, transformations of reaction intermediates within minutes, and a simple route to the rarely observed monoclinic form of the Pharmaceutical cocrystal of carbamazepine and saccharin.
References
More filters
Journal ArticleDOI
A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
Journal ArticleDOI
A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
Journal ArticleDOI
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
Journal ArticleDOI
Asymmetric enamine catalysis.
Journal ArticleDOI
Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.