Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
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Mechanochemical Activation of Iron Cyano Complexes: A Prebiotic Impact Scenario for the Synthesis of α‐Amino Acid Derivatives
Carsten Bolm,Rita Mocci,Christian Schumacher,Mathias Turberg,Francesco Puccetti,Francesco Puccetti,José G. Hernández +6 more
TL;DR: This prebiotic impact scenario can be extended by mechanochemically transforming the resulting α-aminonitriles into α-amino amides using a chemical route related to early Earth conditions.
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Making by Grinding: Mechanochemistry Boosts the Development of Halide Perovskites and Other Multinary Metal Halides
TL;DR: In this paper, the authors focus on mechanochemical synthesis of compounds enabled by grinding or milling of their precursors, following the reaction: AA(ss) + BB(ss), MMMMMM �⎯� AABB(ss).
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Quantitative in situ and real-time monitoring of mechanochemical reactions.
Ivan Halasz,Tomislav Friščić,Simon A. J. Kimber,Krunoslav Užarević,Andreas Puškarić,Cristina Mottillo,Patrick A. Julien,Vjekoslav Štrukil,Veijo Honkimäki,Robert E. Dinnebier +9 more
TL;DR: The first attempts to perform reaction monitoring in a quantitative fashion, by introducing an internal X-ray diffraction standard, are described, allowing the first quantitative estimate of the amorphous phase content in a mechanochemical reaction as it is being milled.
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An inexpensive and recyclable silver-foil catalyst for the cyclopropanation of alkenes with diazoacetates under mechanochemical conditions.
Longrui Chen,Mark O. Bovee,Betsegaw E. Lemma,Kimberlee Keithley,Sara L. Pilson,Michael G. Coleman,James Mack +6 more
TL;DR: This solvent-free method displays analogous reactivity and selectivity to solution-phase reactions without the need for slow diazoacetate addition or an inert atmosphere.
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Intrinsic defect engineering in graphitic carbon nitride for photocatalytic environmental purification: A review to fill existing knowledge gaps
TL;DR: In this paper, the authors highlight the crucial roles of intrinsic defect engineering in the photocatalytic process of metal-free graphitic carbon nitride (g-C3N4) for the first time.
References
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A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
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A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
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Asymmetric enamine catalysis.
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Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.