Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
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A new Cd based metal–organic framework for quick and convenient detection of trace water in isopropanol and 1,4-dioxane
Feng Cheng,Feng Cheng,Ruibiao Fu,Yuehong Wen,Yu-Ying Yang,Chen Zeng,Yu-Xiao Zhang,Shengmin Hu,Xintao Wu +8 more
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Current challenges and future perspectives in sustainable mechanochemical transformations of carbohydrates
TL;DR: The use of mechanochemistry in carbohydrate chemistry is currently a growing field in which many new developments are being made because of its potential application in green methodologies as mentioned in this paper, and the combination of the promising properties of mechanochemical with carbohydrate reactions can be advantageous for setting strategies aligned with the green chemistry principles.
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Synthesis of monosubstituted thioureas by vapour digestion and mechanochemical amination of thiocarbamoyl benzotriazoles
TL;DR: In this article, the authors quantitatively converted Thiocarbamoyl benzotriazoles to N-monosubstituted primary thioureas by vapour digestion under an ammonia atmosphere.
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Nanocasting in ball mills – combining ultra-hydrophilicity and ordered mesoporosity in carbon materials
TL;DR: In this article, a novel carbon material with an ultra-hydrophilic surface and an ordered arrangement of uniformly sized mesopores is synthesized via a solvent-free nanocasting approach conducted in a planetary ball mill.
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Recent developments in next generation (S)-proline-derived chiral organocatalysts
TL;DR: In this paper, an overview of the development of diamine analogs of privileged (S)-prolinols as organocatalysts is presented, and the remarkable influence of solvate ionic liquids as well as the usage of other types of ionic liquid that results in a significant improvement of the catalytic activity of proline is described.
References
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A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
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