Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
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In(III) triflate-mediated solvent-free synthesis and activation of thioglycosides by ball milling and structural analysis of long chain alkyl thioglycosides by TEM and quantum chemical methods.
TL;DR: The distinctly different self-assembling features of the peracetylated octadecyl 1-thio-α- and β-D-galactopyranosides observed by TEM could be rationalized by molecular modeling.
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Enhancing the Pharmaceutical Properties of Pirfenidone by Mechanochemical Cocrystallization
Nimmy Kumari,Biswajit Bhattacharya,Parag Roy,Adam A. L. Michalchuk,Franziska Emmerling,Animesh Ghosh +5 more
TL;DR: Pirfenidone is an important drug molecule used in the treatment of idiopathic lung fibrosis, but although approved by the USFDA in 2014, its aqueous solubility is too high and must be mitigat...
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Mechanochemical and solution synthesis, X-ray structure and IR and 31P solid state NMR spectroscopic studies of copper(I) thiocyanate adducts with bulky monodentate tertiary phosphine ligands
Graham A. Bowmaker,John V. Hanna,Robert D. Hart,Peter Conrad Healy,Scott P. King,Fabio Marchetti,Claudio Pettinari,Brian W. Skelton,Aurel Tăbăcaru,Allan H. White +9 more
TL;DR: The IR spectroscopic measurements on these compounds show that bands in the far-IR spectra provide a much more definitive criterion for distinguishing between bridging and terminal bonding than does an often-used empirical rule based on ν(CN) in the mid-IR, which leads to the wrong conclusion in some cases.
Journal ArticleDOI
Metal-organic frameworks in cooling and water desalination: Synthesis and application
Ramy H. Mohammed,Ahmed Rezk,Ahmed A. Askalany,Ehab S. Ali,A.E. Zohir,Muhammad Sultan,Mohamed Ghazy,Mohammad Ali Abdelkareem,Mohammad Ali Abdelkareem,Abdul Ghani Olabi,Abdul Ghani Olabi +10 more
TL;DR: In this paper, a comprehensive survey of metal-organic frameworks (MOFs) adsorbents and their roles in cooling and water desalination systems is presented, where three aspects are covered, the synthesis processes, the adsorption characteristics, and the implementation of MOFs at the system level.
Journal ArticleDOI
Cocrystal formation by ionic liquid-assisted grinding: case study with cocrystals of caffeine
TL;DR: In this article, liquid assisted grinding using imidazolium-based ionic liquids (IL-AG) was found to be effective in isolation of cocrystals and cocrystal polymorphs.
References
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A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
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A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
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Asymmetric enamine catalysis.
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Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.