Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
Citations
More filters
Journal ArticleDOI
Sustainable Synthesis of a Potent and Selective 5-HT7 Receptor Antagonist Using a Mechanochemical Approach.
TL;DR: A mechanochemical procedure was developed to obtain PZ-1361, a potent and selective 5-HT7 receptor antagonist, with antidepressant properties in rodents, which represents a rare example of the synthesis of biologically active compounds exclusively performed using mechanochemical reactions.
Journal ArticleDOI
Ex situ and in situ monitoring of the syntheses of thermochromic Schiff bases
Marija Zbačnik,Branko Kaitner +1 more
TL;DR: Schiff bases derived from o-hydroxy aldehydes were obtained by mechanochemical synthetic methods with a liquid or a paste present as an intermediate phase as discussed by the authors, and the effectiveness of this procedure was monitored by means of ex situ PXRD and DSC.
Book ChapterDOI
Mechanochemical Reactions of Metal-Organic Frameworks
Yu Run Miao,Kenneth S. Suslick +1 more
TL;DR: The mechanical properties and mechanochemistry of metal-organic framework solids (MOFs) have been only partially explored in this paper, and the large energies required to induce bond rearrangement during plastic deformation suggests an interesting potential of MOFs for shock wave mitigation applications.
Journal ArticleDOI
A critical review of covalent organic frameworks-based sorbents in extraction methods.
TL;DR: In this paper , the authors summarized some important categories of COFs from the point of view of their design and synthetic strategies, and discussed the potential applications of COF-based sorbents in extraction methods.
Journal ArticleDOI
Solid state transformations of different stoichiometric forms of an organic salt formed from 5-sulfosalicylic acid and hexamethylenetetramine upon dehydration and rehydration
TL;DR: In this paper, the interconversion between the stoichiometric variations of 5-sulfosalicylic acid and hexamethylenetetetramine was investigated, in which the dynamic conversion can be obtained by adding one mole of one of the corresponding crystallizing components (A·2H2O or B) upon grinding.
References
More filters
Journal ArticleDOI
A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
Journal ArticleDOI
A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
Journal ArticleDOI
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
Journal ArticleDOI
Asymmetric enamine catalysis.
Journal ArticleDOI
Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.