Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
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Mechanochemical Post-Polymerization Modification: Solvent-Free Solid-State Synthesis of Functional Polymers
Nuri Ohn,Jeung Gon Kim +1 more
TL;DR: In this article, a series of polymers prepared from 4-vinylbenzaldehyde (4-VBA) underwent solid-state Schiff base formation with a series amines and amine derivatives, which not only promoted rapid imine formation but also eliminated the need for a chemical solvent.
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Mechanochemical dehydrochlorination and chelation reaction in the solid state: from a molecular salt to a coordination complex
TL;DR: In this article, the solid state structural transformation of a hydrogen-bonded complex salt into a metal complex via dehydrochlorination using mechanochemistry has been reported and the irreversibility property of the transformation of the coordination complex into a hydrogen bonded complex salt was determined experimentally.
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Densification behaviour and mechanical properties of B4C–SiC intergranular/intragranular nanocomposites fabricated through spark plasma sintering assisted by mechanochemistry
Xiaorong Zhang,Zhixiao Zhang,Weimin Wang,Hongwei Che,Xiaoliang Zhang,Yongmei Bai,Lina Zhang,Zhengyi Fu +7 more
TL;DR: In this article, high performance B 4 C-SiC nanocomposites with intergranular/intragranular structure were fabricated through spark plasma sintering assisted by mechanochemistry with B4 C, Si and graphite powders as raw materials.
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One-pot multistep mechanochemical synthesis of fluorinated pyrazolones
TL;DR: A methodical process to run one solventless reaction directly into another through multistep mechanochemistry, effectively amplifying the solvent savings, resulting in 12 difluorinated pyrazolones in moderate to excellent yields.
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Quantitative Solvent-Free Thermal Synthesis of Luminescent Cu(I) Coordination Polymers
TL;DR: The luminescent Cu(I) coordination polymers n (CuI- m) were successfully synthesized by the solvent-free thermal reaction of the metal salt CuI with the organic linkers m, m'-bpy by simple heating at 140 °C, whereby the excess bpy linker was thermally removed by evaporation.
References
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A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
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A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
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Asymmetric enamine catalysis.
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Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.