Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
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Efficient continuous synthesis of high purity deep eutectic solvents by twin screw extrusion
TL;DR: Mechanochemical synthesis has been applied to the rapid synthesis of Deep Eutectic Solvents, including Reline 200, in a continuous flow methodology by Twin Screw Extrusion (TSE), which gave products in higher purity and with Space Time Yields (STYs), four orders of magnitude greater than for batch methods.
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Mechanochemical C–H bond activation: rapid and regioselective double cyclopalladation monitored by in situ Raman spectroscopy
TL;DR: The first direct mechanochemical transition-metal-mediated activation of strong phenyl C-H bonds is reported, resulting in cyclopalladated complexes that are quantitative and significantly faster than solution synthesis.
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Mechanochemical Synthesis of Multicomponent Crystals: One Liquid for One Polymorph? A Myth to Dispel
TL;DR: In this paper, the amount of liquid present during liquid-assisted mechanochemical reactions can be used to rapidly explore polymorph diversity for a specific (multicomponent) crystal system investigated (caffeine-anthranilic acid).
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Fast fluoride ion conducting materials in solid state ionics: An overview
TL;DR: In this article, a brief overview of synthesis and application aspects of fast fluoride ion conducting materials in the field of solid state ionics is presented, along with possible technological applications of fast fluoride ion conducting material in different solid-state ionic devices.
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Nonequilibrium structure of Zn2SnO4 spinel nanoparticles
Vladimir Šepelák,Vladimir Šepelák,Sebastian M. Becker,Ingo Bergmann,Sylvio Indris,Marco Scheuermann,Armin Feldhoff,Christian Kübel,Michael Bruns,Ninette Stürzl,Anne S. Ulrich,Mohammad Ghafari,Horst Hahn,Clare P. Grey,Clare P. Grey,Klaus Becker,Klaus Becker,Paul Heitjans +17 more
TL;DR: In this paper, high-resolution TEM studies reveal a non-uniform structure of mechanosynthesized Zn2SnO4 nanoparticles consisting of a crystalline core surrounded by a structurally disordered surface shell.
References
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A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
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A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
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Asymmetric enamine catalysis.
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Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.