Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
Citations
More filters
Journal ArticleDOI
Rapid and facile solvent-free mechanosynthesis in a cell lysis mill: preparation and mechanochemical complexation of aminobenzoquinones
TL;DR: In this article, a cell lysis mill, typically used for the breakdown of biological structures in microbiological and biochemical studies, was used as a tool for rapid, solvent-free and general synthesis of short and long-chain substituted zwitterionic meta- and para-aminobenzoquinones, never previously prepared under solvent free conditions.
Journal ArticleDOI
Processing of thermally stable 3D hierarchical ZIF-8@ZnO structures and their CO2 adsorption studies
Minju Thomas,Minju Thomas,Balagopal N. Nair,Gopinathan M. Anilkumar,A. Peer Mohamed,Krishna Gopakumar Warrier,Unnikrishnan Nair Saraswathy Hareesh,Unnikrishnan Nair Saraswathy Hareesh +7 more
TL;DR: In this paper, the surface area and pore volume of ZnO-Zeolitic Imidazolate Framework-8 (ZIF@ZnO) structures were obtained by the solvothermal treatment of hierarchical structures having an average cluster size of ∼3μm and surface area of ∼19m 2 /g.
Journal ArticleDOI
Playing with Isomerism: Cocrystallization of Isomeric N-Salicylideneaminopyridines with Perfluorinated Compounds as Halogen Bond Donors and Its Impact on Photochromism
Andrea Carletta,Marija Zbačnik,Mégane Van Gysel,Matea Vitković,Nikolay Tumanov,Vladimir Stilinović,Johan Wouters,Dominik Cinčić +7 more
TL;DR: In this article, the authors focus on cocrystals of isomeric N-salicylideneaminopyridines with perfluorinated halogen bond donors as coformers.
Journal ArticleDOI
Solvent and catalyst free synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones by twin screw extrusion
TL;DR: In this article, the synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones using a twin screw extruder was described.
Journal ArticleDOI
Exploring the structural landscape of 2-aminopyrazines via co-crystallizations
TL;DR: In this article, a correlation between the electrostatic charge on the acceptor sites of 2-aminopyrazine derivatives and the ability of the compound to form intermolecular hydrogen bonds with carboxylic acids in the solid state has been established.
References
More filters
Journal ArticleDOI
A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
Journal ArticleDOI
A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
Journal ArticleDOI
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
Journal ArticleDOI
Asymmetric enamine catalysis.
Journal ArticleDOI
Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.