Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James,Christopher J. Adams,Carsten Bolm,Dario Braga,Paul Collier,Tomislav Friščić,Fabrizia Grepioni,Kenneth D. M. Harris,Geoff Hyett,William Jones,Anke Krebs,James Mack,Lucia Maini,A. Guy Orpen,Ivan P. Parkin,William C. Shearouse,Jonathan W. Steed,Daniel C. Waddell +17 more
TLDR
Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes, supramolecular aspects and characterization methods.Abstract:
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).read more
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Mechanosynthesis of amides in the total absence of organic solvent from reaction to product recovery
Thomas-Xavier Métro,Julien Bonnamour,Thomas Reidon,Jordi Sarpoulet,Jean Martinez,Frédéric Lamaty +5 more
TL;DR: The synthesis of various amides has been realised avoiding the use of any organic solvent from activation of carboxylic acids with CDI to isolation of the amides.
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MgO modified biochar produced through ball milling: A dual-functional adsorbent for removal of different contaminants.
TL;DR: This work indicates that ball milling, as a facile and promising method for synthesis of carbon-metal oxide nanocomposites, lends the advantage of operational flexibility and chemical adjustability for targeted remediation of diverse environmental pollutants.
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Multi-step and multi-component organometallic synthesis in one pot using orthogonal mechanochemical reactions
TL;DR: In this paper, the authors demonstrate that the mechanochemical strategies for oxidative addition and ligand substitution on organometallic centers can be mutually orthogonal, permitting the rational design of multi-component mechanochemical reaction procedures for assembling complex or solution-sensitive organometallics from three, four or even five components in one pot.
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Nanoscale covalent organic frameworks as theranostic platforms for oncotherapy: synthesis, functionalization, and applications
TL;DR: Covalent organic frameworks (COFs) are becoming an attractive class of upstarts owing to their high crystallinity, structural regularity, inherent porosity, extensive functionality, design flexibility, and good biocompatibility as mentioned in this paper.
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Ferrofluids: Synthetic Strategies, Stabilization, Physicochemical Features, Characterization, and Applications
Aswathy Joseph,Suresh Mathew +1 more
TL;DR: A comprehensive review on the different aspects of Ferrofluids research is presented in this paper, where the synthesis and stabilization of various types of FFs are discussed followed by their physicochemical features such as polydispersity, magnetic behavior, dipolar interactions, formation of chainlike aggregates, and long-range ordering.
References
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A profile refinement method for nuclear and magnetic structures
TL;DR: In this paper, a structure refinement method was described which does not use integrated neutron powder intensities, single or overlapping, but employs directly the profile intensities obtained from step-scanning measurements of the powder diagram.
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A chemically functionalizable nanoporous material (Cu3(TMA)2(H2O)3)n
TL;DR: In this paper, a highly porous metal coordination polymer [Cu3(TMA)2(H2O)3]n (where TMA is benzene-1,3,5-tricarboxylate) was formed in 80 percent yield.
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
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Asymmetric enamine catalysis.
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Rietveld refinement guidelines
TL;DR: A set of general guidelines for structure refinement using the Rietveld (whole profile) method has been formulated by the International Union of Crystallography Commission on Powder Diffraction.