Journal ArticleDOI
Neuroanatomical abnormalities in schizophrenia: a multimodal voxelwise meta-analysis and meta-regression analysis.
Emre Bora,Alex Fornito,Joaquim Radua,Mark Walterfang,Marc L. Seal,Stephen J. Wood,Stephen J. Wood,Murat Yücel,Dennis Velakoulis,Christos Pantelis +9 more
TLDR
The meta-analyses revealed overlapping GM and WM structural findings in schizophrenia, characterized by bilateral anterior cortical, limbic and subcortical GM abnormalities, and WM changes in regions including tracts that connect these structures within and between hemispheres.About:
This article is published in Schizophrenia Research.The article was published on 2011-04-01. It has received 405 citations till now. The article focuses on the topics: Voxel-based morphometry & Fornix.read more
Citations
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Journal ArticleDOI
Identification of a common neurobiological substrate for mental illness.
Madeleine S. Goodkind,Simon B. Eickhoff,Desmond J. Oathes,Desmond J. Oathes,Ying Jiang,Ying Jiang,Andrew Chang,Andrew Chang,Laura B. Jones-Hagata,Laura B. Jones-Hagata,Brissa N. Ortega,Brissa N. Ortega,Yevgeniya V. Zaiko,Yevgeniya V. Zaiko,Erika L. Roach,Erika L. Roach,Mayuresh S. Korgaonkar,Stuart M. Grieve,Isaac R. Galatzer-Levy,Peter T. Fox,Amit Etkin,Amit Etkin +21 more
TL;DR: A concordance is identified in terms of integrity of an anterior insula/dorsal anterior cingulate-based network, which may relate to executive function deficits observed across diagnoses, which provides an organizing model that emphasizes the importance of shared neural substrates across psychopathology.
Journal ArticleDOI
Gray matter abnormalities in Major Depressive Disorder: A meta-analysis of voxel based morphometry studies
TL;DR: The associations between these gray matter anomalies and clinical characteristics, particularly measures relating to illness duration, suggest that chronic MDD has a robust and deleterious, albeit spatially focal, effect on brain structure.
Journal ArticleDOI
CNVs conferring risk of autism or schizophrenia affect cognition in controls
Hreinn Stefansson,Andreas Meyer-Lindenberg,Stacy Steinberg,Brynja B. Magnusdottir,Katrin Morgen,Sunna Arnarsdottir,Gyda Bjornsdottir,G. Bragi Walters,Gudrun A. Jonsdottir,Orla Doyle,Heike Tost,Oliver Grimm,Solveig Kristjansdottir,Heimir Snorrason,Solveig Davidsdottir,Larus J. Gudmundsson,Gudbjorn F. Jonsson,Berglind Stefansdottir,Isafold Helgadottir,Magnús Haraldsson,Birna Jonsdottir,Johan H. Thygesen,Adam J. Schwarz,Michael Didriksen,Tine B. Stensbøl,Michael Brammer,Shitij Kapur,Jonas G. Halldorsson,Stefan Hreidarsson,Evald Saemundsen,Engilbert Sigurdsson,Kari Stefansson +31 more
TL;DR: It is shown in an Icelandic sample that a few of the CNVs clearly alter fecundity (measured as the number of children by age 45), and various tests of cognitive function are used to demonstrate that control subjects carrying theCNVs perform at a level that is between that of schizophrenia patients and population controls.
Journal ArticleDOI
A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps
Joaquim Radua,David Mataix-Cols,Mary L. Phillips,Mary L. Phillips,Wissam El-Hage,Dina M. Kronhaus,Narcís Cardoner,Simon Surguladze +7 more
TL;DR: In this paper, a new signed differential mapping (SDM) method was proposed, called Effect Size SDM (ES-SDM), which enables the combination of statistical parametric maps and peak coordinates and uses well-established statistics.
Journal ArticleDOI
Widespread white matter microstructural differences in schizophrenia across 4322 individuals : results from the ENIGMA Schizophrenia DTI Working Group
Sinead Kelly,Sinead Kelly,Neda Jahanshad,Andrew Zalesky,Peter Kochunov,Ingrid Agartz,Ingrid Agartz,Clara Alloza,Ole A. Andreassen,Celso Arango,Nerisa Banaj,Sylvain Bouix,Chad A. Bousman,Chad A. Bousman,Chad A. Bousman,Rachel M. Brouwer,Jason M. Bruggemann,Juan R. Bustillo,Wiepke Cahn,V.D. Calhoun,V.D. Calhoun,Dara M. Cannon,Vaughan J. Carr,Stanley V. Catts,J. Chen,J. X. Chen,X. Chen,Chiara Chiapponi,Kl K. Cho,Valentina Ciullo,A. S. Corvin,Benedicto Crespo-Facorro,Vanessa Cropley,P. De Rossi,Covadonga M. Díaz-Caneja,Erin W. Dickie,Stefan Ehrlich,F. M. Fan,Joshua Faskowitz,Helena Fatouros-Bergman,L. Flyckt,L. Flyckt,Judith M. Ford,Jean-Paul Fouche,Masaki Fukunaga,Michael Gill,David C. Glahn,Randy L. Gollub,E. D. Goudzwaard,H. Guo,R.E. Gur,Ruben C. Gur,Tiril P. Gurholt,Ryota Hashimoto,Ryota Hashimoto,Sean N. Hatton,Frans Henskens,Frans Henskens,Derrek P. Hibar,Ian B. Hickie,L. E. Hong,Jiri Horacek,Jiri Horacek,Fleur M. Howells,Hilleke E. Hulshoff Pol,Craig L. Hyde,Dmitry Isaev,Assen Jablensky,Philip R. Jansen,Joost Janssen,Joost Janssen,Erik G. Jönsson,Erik G. Jönsson,L. A. Jung,René S. Kahn,Zora Kikinis,K. Liu,Paul Klauser,Paul Klauser,Paul Klauser,C. Knöchel,Marek Kubicki,Jim Lagopoulos,Carolyn D. Langen,Stephen M. Lawrie,Rhoshel K. Lenroot,Kelvin O. Lim,Carlos López-Jaramillo,Amanda E. Lyall,Amanda E. Lyall,Vincent A. Magnotta,René C.W. Mandl,Daniel H. Mathalon,R. W. McCarley,Simon McCarthy-Jones,Colm McDonald,Sarah McEwen,Andrew M. McIntosh,Tomas Melicher,Tomas Melicher,Raquelle I. Mesholam-Gately,Patricia T. Michie,Patricia T. Michie,Bryan J. Mowry,Bryon A. Mueller,Dominick T. Newell,Patricio O'Donnell,V. Oertel-Knöchel,Lena K. L. Oestreich,Sara A. Paciga,Christos Pantelis,Christos Pantelis,Christos Pantelis,Ofer Pasternak,Godfrey D. Pearlson,Gaia Romana Pellicano,Antonio Pereira,J. Pineda Zapata,F. Piras,Steven G. Potkin,Adrian Preda,P. E. Rasser,P. E. Rasser,David R. Roalf,R. Roiz,Annerine Roos,D. Rotenberg,Theodore D. Satterthwaite,Peter Savadjiev,Ulrich Schall,Ulrich Schall,Rodney J. Scott,Rodney J. Scott,Marc L. Seal,Larry J. Seidman,Larry J. Seidman,Larry J. Seidman,C. Shannon Weickert,C. Shannon Weickert,C. Shannon Weickert,Christopher D. Whelan,Martha E. Shenton,Martha E. Shenton,Jun Soo Kwon,Gianfranco Spalletta,Filip Spaniel,Filip Spaniel,Emma Sprooten,M. Stäblein,Dan J. Stein,Dan J. Stein,Suresh Sundram,Suresh Sundram,Y. Tan,S. Tan,S. Tang,H. S. Temmingh,Lars T. Westlye,Siren Tønnesen,Diana Tordesillas-Gutiérrez,Nhat Trung Doan,Jatin G. Vaidya,N.E.M. van Haren,Claudia D. Vargas,Daniela Vecchio,Dennis Velakoulis,Aristotle N. Voineskos,J. Q. Voyvodic,Zhen Wang,P. Wan,D. Wei,Thomas W. Weickert,Thomas W. Weickert,Thomas W. Weickert,Heather C. Whalley,Tonya White,Thomas J. Whitford,Joanne Wojcik,H. Xiang,H. Xiang,Z. Xie,H. Yamamori,F. Yang,Nailin Yao,G. Zhang,Jingjing Zhao,Jingjing Zhao,T.G.M. van Erp,Jessica A. Turner,Paul M. Thompson,Paul M. Thompson,Gary Donohoe +191 more
TL;DR: The present study provides a robust profile of widespread WM abnormalities in schizophrenia patients worldwide, and is believed to be the first ever large-scale coordinated study of WM microstructural differences in schizophrenia.
References
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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal ArticleDOI
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
TL;DR: PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is introduced, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses.
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Voxel-Based Morphometry—The Methods
John Ashburner,Karl J. Friston +1 more
TL;DR: In this paper, the authors describe the steps involved in VBM, with particular emphasis on segmenting gray matter from MR images with non-uniformity artifact and provide evaluations of the assumptions that underpin the method, including the accuracy of the segmentation and the assumptions made about the statistical distribution of the data.
Journal ArticleDOI
A voxel-based morphometric study of ageing in 465 normal adult human brains.
Catriona D. Good,Ingrid S. Johnsrude,John Ashburner,Richard N. Henson,Richard N. Henson,Karl J. Friston,Richard S. J. Frackowiak +6 more
TL;DR: Global grey matter volume decreased linearly with age, with a significantly steeper decline in males, and local areas of accelerated loss were observed bilaterally in the insula, superior parietal gyri, central sulci, and cingulate sulci.